Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11929608 | 0.74 | TP53 (0.50) | SMN1; SMN2TP53PREPALDH1A1KMT2A | |
| SCHEMBL13618223 | 0.73 | ALDH1A1 (0.54) | TSHRSMN1; SMN2TP53ALDH1A1KMT2A | |
| SCHEMBL21137267 | 0.73 | SMN1; SMN2 (0.45) | TSHRSMN1; SMN2TP53ALDH1A1KMT2A | |
| SCHEMBL18908668 | 0.72 | SMN1; SMN2 (0.59) | SMN1; SMN2TP53ALDH1A1KMT2AHPGD | |
| SCHEMBL18685664 | 0.71 | TSHR (0.53) | TSHRSMN1; SMN2TP53ALDH1A1KMT2A | |
| SCHEMBL11890389 | 0.70 | EPHX1 (0.48) | SMN1; SMN2TP53PREPHPGDRAB9A | |
| SCHEMBL9575 | 0.69 | EPHX1 (0.52) | SMN1; SMN2ALDH1A1HPGDRAB9AEPHX1 | |
| SCHEMBL25083177 | 0.69 | TSHR (0.45) | TSHRSMN1; SMN2TP53ALDH1A1KMT2A | |
| SCHEMBL22338220 | 0.69 | TSHR (0.45) | TSHRSMN1; SMN2TP53ALDH1A1KMT2A | |
| SCHEMBL16674468 | 0.69 | TP53 (0.45) | SMN1; SMN2TP53PREPALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017053586-A1 | DEVICE, SYSTEM AND METHOD FOR USING THE DEVICE OR SYSTEM FOR ASSAYING AN ANALYTE IN A SAMPLE | CEDARS-SINAI MEDICAL CENTER (US) | 2017-03-30 | — | — | WO | disclosed |