Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.44 |
| ▸ | HTR2B | P41595 | 3/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1350516 | 0.79 | MEN1 (0.50) | HTR2CHTR2BSIGMAR1HTR3EHTR3B | |
| SCHEMBL2017872 | 0.78 | DRD2 (0.41) | HTR2CHTR2BSIGMAR1MAPTALDH1A1 | |
| SCHEMBL23469285 | 0.72 | HTR3E (0.46) | HTR2CHTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL11822257 | 0.68 | HTR2C (0.51) | HTR2CHTR2BSIGMAR1MAPTALDH1A1 | |
| SCHEMBL2565554 | 0.68 | DRD2 (0.44) | HTR2CHTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL11818669 | 0.68 | HTR2C (0.51) | HTR2CHTR2BSIGMAR1HTR6 | |
| SCHEMBL16565924 | 0.67 | HTR2B (0.40) | HTR2CHTR2BNPSR1 | |
| SCHEMBL5871641 | 0.66 | HTR2C (0.65) | HTR2CHTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL26675973 | 0.65 | HTR2C (0.60) | HTR2CHTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL11446133 | 0.64 | MEN1 (0.60) | HTR2CHTR2BSIGMAR1HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150607-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | AbbVie Inc. (US) | 2017-04-05 | — | — | EP | disclosed |