Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 5/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2124067 | 0.93 | MAPT (0.44) | CSNK2A1EGFRERBB2PRKCQMAPT | |
| SCHEMBL18686166 | 0.92 | CSNK2A1 (0.45) | CSNK2A1EGFRERBB2GSK3BCDC25B | |
| SCHEMBL15266840 | 0.92 | CSNK2A1 (0.40) | CSNK2A1EGFRERBB2PRKCQGSK3B | |
| SCHEMBL2123139 | 0.88 | EGFR (0.50) | CSNK2A1EGFRERBB2ALDH1A1 | |
| SCHEMBL18686158 | 0.88 | CSNK2A1 (0.42) | CSNK2A1EGFRERBB2GSK3BCDC25B | |
| SCHEMBL2123272 | 0.88 | MAPT (0.41) | CSNK2A1EGFRERBB2PRKCQMAPT | |
| SCHEMBL2124193 | 0.86 | MAPT (0.41) | CSNK2A1EGFRERBB2PRKCQCDC25B | |
| SCHEMBL2124547 | 0.85 | MAPT (0.42) | CSNK2A1EGFRERBB2MAPTALDH1A1 | |
| SCHEMBL18686168 | 0.84 | CSNK2A1 (0.43) | CSNK2A1EGFRERBB2PRKCQ | |
| SCHEMBL18686155 | 0.84 | CSNK2A1 (0.43) | CSNK2A1EGFRERBB2PRKCQXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443123-B1 | SMALL MOLECULE INHIBITORS OF SPLEEN TYROSINE KINASE (SYK) | RIGEL PHARMACEUTICALS INC (US) | 2017-04-05 | — | — | EP | claimed |