Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 9/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18686156 | 0.94 | MPO (0.39) | CSNK2A1PRKCQMPOEGFRERBB2 | |
| SCHEMBL2125521 | 0.93 | PRKCQ (0.42) | CSNK2A1PRKCQEGFRERBB2SRC | |
| SCHEMBL2125564 | 0.93 | PRKCQ (0.42) | CSNK2A1PRKCQEGFRERBB2SRC | |
| SCHEMBL18686170 | 0.93 | CSNK2A1 (0.42) | CSNK2A1PRKCQMPOEGFRERBB2 | |
| SCHEMBL2122009 | 0.92 | PRKCQ (0.42) | CSNK2A1PRKCQEGFRERBB2SRC | |
| SCHEMBL2124351 | 0.89 | PRKCQ (0.39) | CSNK2A1PRKCQEGFRERBB2SRC | |
| SCHEMBL2124008 | 0.89 | PRKCQ (0.44) | CSNK2A1PRKCQEGFRERBB2SRC | |
| SCHEMBL2123272 | 0.88 | MAPT (0.41) | CSNK2A1PRKCQMPOEGFRERBB2 | |
| SCHEMBL2123878 | 0.88 | ALDH1A1 (0.45) | CSNK2A1PRKCQADORA2BADORA2AHPGD | |
| SCHEMBL2125445 | 0.88 | PRKCQ (0.38) | CSNK2A1PRKCQEGFRERBB2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443123-B1 | SMALL MOLECULE INHIBITORS OF SPLEEN TYROSINE KINASE (SYK) | RIGEL PHARMACEUTICALS INC (US) | 2017-04-05 | — | — | EP | claimed |