Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.35 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | SDCBP | O00560 | 2/20 | 0.33 |
| ▸ | SDC2 | P34741 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13078540 | 0.85 | PLA2G10 (0.45) | MAPTHSD17B10PLA2G2APLA2G5PLA2G10 | |
| SCHEMBL18668921 | 0.84 | PLA2G2C (0.38) | MAPTHSD17B10PLA2G2APLA2G5TSHR | |
| SCHEMBL18686282 | 0.84 | PLA2G2C (0.38) | MAPTHSD17B10PLA2G2APLA2G5TSHR | |
| SCHEMBL10274720 | 0.83 | MAPT (0.45) | MAPTHSD17B10PLA2G2APLA2G5PLA2G10 | |
| SCHEMBL18668999 | 0.83 | SMN1; SMN2 (0.37) | MAPTHSD17B10PLA2G2APLA2G5TSHR | |
| SCHEMBL10274648 | 0.83 | MAPT (0.45) | MAPTHSD17B10PLA2G2APLA2G5PLA2G10 | |
| SCHEMBL22206203 | 0.83 | SMN1; SMN2 (0.37) | MAPTHSD17B10PLA2G2APLA2G5TSHR | |
| SCHEMBL21074188 | 0.83 | SMN1; SMN2 (0.37) | MAPTHSD17B10PLA2G2APLA2G5TSHR | |
| SCHEMBL27030977 | 0.79 | TSHR (0.37) | HSD17B10TSHRALDH1A1AKR1B1EPHX2 | |
| SCHEMBL19323020 | 0.78 | CYP2C9 (0.41) | MAPTHSD17B10BIRC2ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119539-A1 | PRODRUGS OF GAMMA-HYDROXYBUTYRIC ACID, COMPOSITIONS AND USES THEREOF | XWPharma Ltd. (KY) | 2023-01-18 | — | — | EP | disclosed |
| WO-2017050259-A1 | PRODRUGS OF GAMMA-HYDROXYBUTYRIC ACID, COMPOSITIONS AND USES THEREOF | XW LABORATORIES INC. (KY) | 2017-03-30 | — | — | WO | disclosed |