Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.40 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10274648 | 1.00 | MAPT (0.45) | MAPTHSD17B10PLA2G10PLA2G2CMEN1 | |
| SCHEMBL13078540 | 0.93 | PLA2G10 (0.45) | MAPTHSD17B10PLA2G10PLA2G2CMEN1 | |
| SCHEMBL8365711 | 0.89 | MAPT (0.48) | MAPTHSD17B10MEN1FAAHMAPK1 | |
| SCHEMBL16116959 | 0.86 | FAAH (0.57) | MAPTHSD17B10PLA2G10PLA2G2CMEN1 | |
| SCHEMBL16116961 | 0.86 | FAAH (0.57) | MAPTHSD17B10PLA2G10PLA2G2CMEN1 | |
| SCHEMBL21118578 | 0.84 | PLA2G10 (0.44) | MAPTHSD17B10PLA2G10PLA2G2CMEN1 | |
| SCHEMBL16116967 | 0.83 | FAAH (0.57) | PLA2G10PLA2G2CMEN1FAAHMAPK1 | |
| SCHEMBL16116972 | 0.83 | FAAH (0.57) | PLA2G10PLA2G2CMEN1FAAHMAPK1 | |
| SCHEMBL16116971 | 0.83 | FAAH (0.57) | PLA2G10PLA2G2CMEN1FAAHMAPK1 | |
| SCHEMBL18686238 | 0.83 | MAPT (0.37) | MAPTHSD17B10PLA2G10PLA2G2APLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046062-A1 | USE OF PRODRUGS TO AVOID GI MEDIATED ADVERSE EVENTS | SHIRE, LLC (US) | 2012-04-12 | — | — | WO | disclosed |
| US-20100286186-A1 | NOVEL DICARBOXYLIC ACID LINKED AMINO ACID AND PEPTIDE PRODRUGS OF OPIOIDS AND USES THEREOF | SHIRE LLC (US) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286186-A1 | NOVEL DICARBOXYLIC ACID LINKED AMINO ACID AND PEPTIDE PRODRUGS OF OPIOIDS AND USES THEREOF | VIP, OPRL1, OPRK1 | MAPT 1430/4885HSD17B10 2305/4885PLA2G10 4642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.