SCHEMBL21074188

SCHEMBL21074188

CCOC(=O)NC(C(=O)OCCCC(=O)O)C(C)C

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.37
MAPK1 P28482 1/20 0.37
MAPT P10636 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TYR P14679 1/20 0.35
EPHX2 P34913 2/20 0.35
PLA2G2A P14555 1/20 0.34
PLA2G5 P39877 1/20 0.34
LMNA P02545 1/20 0.34
HTT P42858 1/20 0.34
TSHR P16473 1/20 0.33
CTSB P07858 1/20 0.33
CTSK P43235 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18668999 1.00 SMN1; SMN2 (0.37) SMN1; SMN2MAPK1MAPTHSD17B10TYR
SCHEMBL22206203 1.00 SMN1; SMN2 (0.37) SMN1; SMN2MAPK1MAPTHSD17B10TYR
SCHEMBL23331939 0.83 ACHE (0.43) SMN1; SMN2MAPK1MAPTHSD17B10TYR
SCHEMBL18686238 0.83 MAPT (0.37) SMN1; SMN2MAPTHSD17B10EPHX2PLA2G2A
SCHEMBL18668921 0.83 PLA2G2C (0.38) MAPTHSD17B10PLA2G2APLA2G5TSHR
SCHEMBL18686282 0.83 PLA2G2C (0.38) MAPTHSD17B10PLA2G2APLA2G5TSHR
SCHEMBL3729786 0.82 CTSK (0.51) CTSBCTSK
SCHEMBL18668909 0.82 CTSK (0.51) CTSBCTSK
SCHEMBL13039839 0.82 CTSK (0.51) CTSBCTSK
SCHEMBL24938388 0.82 SMN1; SMN2 (0.37) SMN1; SMN2MAPK1MAPTHSD17B10TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115803017-A Pharmaceutical granulation of water-soluble active pharmaceutical ingredients 凯瑞康宁生物工程有限公司 2023-03-14 CN claimed
CN-115038432-A Controlled release granulation of water soluble active pharmaceutical ingredients 凯瑞康宁生物工程(武汉)有限公司 2022-09-09 CN claimed
US-20220183977-A1 CONTROLLED RELEASE GRANULATIONS OF WATER-SOLUBLE ACTIVE PHARMACEUTICAL INGREDIENTS XWPharma Ltd. (KY) 2022-06-16 US claimed
US-11304906-B2 Controlled release granulations of water-soluble active pharmaceutical ingredients XWPharma Ltd. (KY) 2022-04-19 US claimed
US-20210393529-A1 CONTROLLED RELEASE GRANULATIONS OF WATER-SOLUBLE ACTIVE PHARMACEUTICAL INGREDIENTS XWPharma Ltd. (KY) 2021-12-23 US claimed
US-20210393537-A1 PHARMACEUTICAL GRANULATIONS OF WATER-SOLUBLE ACTIVE PHARMACEUTICAL INGREDIENTS XWPharma Ltd. (KY) 2021-12-23 US claimed
US-10774031-B2 Prodrugs of gamma-hydroxybutyric acid, compositions and uses thereof XW LABORATORIES INC. (KY) 2020-09-15 US claimed
US-20200223783-A1 PRODRUGS OF GAMMA-HYDROXYBUTYRIC ACID, COMPOSITIONS AND USES THEREOF XW LABORATORIES INC. (KY) 2020-07-16 US claimed
US-20250262157-A1 CONTROLLED RELEASE GRANULATIONS OF WATER-SOLUBLE ACTIVE PHARMACEUTICAL INGREDIENTS XWPharma Ltd. (KY) 2025-08-21 US disclosed
US-12337066-B2 Controlled release granulations of water-soluble active pharmaceutical ingredients XWPharma Ltd. (KY) 2025-06-24 US disclosed
CN-117618393-A Controlled release granulation of water-soluble active pharmaceutical ingredient 凯瑞康宁生物工程(武汉)有限公司 2024-03-01 CN disclosed
CN-115038432-B Controlled release granulation of water-soluble active pharmaceutical ingredient 凯瑞康宁生物工程(武汉)有限公司 2023-12-26 CN disclosed
CN-115803017-A Pharmaceutical granulation of water-soluble active pharmaceutical ingredients 凯瑞康宁生物工程有限公司 2023-03-14 CN disclosed
US-20220323366-A1 PHARMACEUTICAL GRANULATIONS OF WATER-SOLUBLE ACTIVE PHARMACEUTICAL INGREDIENTS XWPharma Ltd. (KY) 2022-10-13 US disclosed
US-10774031-B2 Prodrugs of gamma-hydroxybutyric acid, compositions and uses thereof XW LABORATORIES INC. (KY) 2020-09-15 US disclosed
US-20200223783-A1 PRODRUGS OF GAMMA-HYDROXYBUTYRIC ACID, COMPOSITIONS AND USES THEREOF XW LABORATORIES INC. (KY) 2020-07-16 US disclosed
US-10640451-B2 Prodrugs of gamma-hydroxybutyric acid, compositions and uses thereof XW LABORATORIES INC. (KY) 2020-05-05 US disclosed
US-10457627-B2 Prodrugs of gamma-hydroxybutyric acid, compositions and uses thereof XW LABORATORIES INC. (KY) 2019-10-29 US disclosed
US-20190218168-A1 PRODRUGS OF GAMMA-HYDROXYBUTYRIC ACID, COMPOSITIONS AND USES THEREOF XWPharma Ltd. (KY) 2019-07-18 US disclosed
US-20190194120-A1 PRODRUGS OF GAMMA-HYDROXYBUTYRIC ACID, COMPOSITIONS AND USES THEREOF XWPharma Ltd. (KY) 2019-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10640451-B2 Prodrugs of gamma-hydroxybutyric acid, compositions and uses thereof GABRB3, GABRB2, GABRB1 SMN1; SMN2 2384/4885MAPK1 4712/4885MAPT 3453/4885
US-12337066-B2 Controlled release granulations of water-soluble active pharmaceutical ingredients GMPS, SI, UGGT1 SMN1; SMN2 3927/4885MAPK1 4614/4885MAPT 2661/4885
US-20210393529-A1 CONTROLLED RELEASE GRANULATIONS OF WATER-SOLUBLE ACTIVE PHARMACEUTICAL INGREDIENTS GMPS, SI, UGGT1 SMN1; SMN2 3927/4885MAPK1 4614/4885MAPT 2661/4885
US-20250262157-A1 CONTROLLED RELEASE GRANULATIONS OF WATER-SOLUBLE ACTIVE PHARMACEUTICAL INGREDIENTS GMPS, SI, UGGT1 SMN1; SMN2 3927/4885MAPK1 4614/4885MAPT 2661/4885
US-10457627-B2 Prodrugs of gamma-hydroxybutyric acid, compositions and uses thereof GABRB3, GABRB2, GABRB1 SMN1; SMN2 2384/4885MAPK1 4712/4885MAPT 3453/4885
US-20190194120-A1 PRODRUGS OF GAMMA-HYDROXYBUTYRIC ACID, COMPOSITIONS AND USES THEREOF GABRB3, GABRB2, GABRB1 SMN1; SMN2 2384/4885MAPK1 4712/4885MAPT 3453/4885
US-20220323366-A1 PHARMACEUTICAL GRANULATIONS OF WATER-SOLUBLE ACTIVE PHARMACEUTICAL INGREDIENTS GMPS, GYS2, SLC18A1 SMN1; SMN2 3367/4885MAPK1 4181/4885MAPT 2638/4885
US-10774031-B2 Prodrugs of gamma-hydroxybutyric acid, compositions and uses thereof GABRB3, GABRB2, GABRB1 SMN1; SMN2 2384/4885MAPK1 4712/4885MAPT 3453/4885
US-20210393537-A1 PHARMACEUTICAL GRANULATIONS OF WATER-SOLUBLE ACTIVE PHARMACEUTICAL INGREDIENTS GMPS, GYS2, SLC18A1 SMN1; SMN2 3367/4885MAPK1 4181/4885MAPT 2638/4885
US-20220183977-A1 CONTROLLED RELEASE GRANULATIONS OF WATER-SOLUBLE ACTIVE PHARMACEUTICAL INGREDIENTS GMPS, SI, UGGT1 SMN1; SMN2 3927/4885MAPK1 4614/4885MAPT 2661/4885
US-11304906-B2 Controlled release granulations of water-soluble active pharmaceutical ingredients GMPS, SI, UGGT1 SMN1; SMN2 3927/4885MAPK1 4614/4885MAPT 2661/4885
US-20190218168-A1 PRODRUGS OF GAMMA-HYDROXYBUTYRIC ACID, COMPOSITIONS AND USES THEREOF GABRB3, GABRB2, GABRB1 SMN1; SMN2 2384/4885MAPK1 4712/4885MAPT 3453/4885
US-20200223783-A1 PRODRUGS OF GAMMA-HYDROXYBUTYRIC ACID, COMPOSITIONS AND USES THEREOF GABRB3, GABRB2, GABRB1 SMN1; SMN2 2384/4885MAPK1 4712/4885MAPT 3453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.