Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 5/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.44 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.44 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5483726 | 0.93 | PLA2G2C (0.44) | PLA2G2CUSP2LPAR1LPAR3HTT | |
| SCHEMBL5480810 | 0.90 | PLA2G2C (0.41) | PLA2G2CUSP2LPAR1LPAR3TLR2 | |
| SCHEMBL5480615 | 0.89 | LPAR1 (0.40) | PLA2G2CLPAR1LPAR3LPAR5LPAR6 | |
| SCHEMBL11294443 | 0.88 | PLA2G2C (0.55) | PLA2G2CUSP2LPAR1LPAR3HTT | |
| SCHEMBL10826349 | 0.88 | GPR84 (0.44) | — | |
| SCHEMBL17744046 | 0.87 | ALDH1A1 (0.49) | LPAR1LPAR3CYP3A4 | |
| SCHEMBL22274219 | 0.87 | ALDH1A1 (0.49) | LPAR1LPAR3CYP3A4 | |
| SCHEMBL17744044 | 0.87 | ALDH1A1 (0.49) | LPAR1LPAR3CYP3A4 | |
| SCHEMBL30227320 | 0.86 | USP2 (0.56) | PLA2G2CUSP2LPAR1LPAR3HTT | |
| SCHEMBL25227883 | 0.85 | GPR84 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3202760-B1 | PEGYLATED LIPIDS AND THEIR USE FOR DRUG DELIVERY | ALNYLAM PHARMACEUTICALS INC (US) | 2019-08-21 | — | — | EP | disclosed |
| US-9999673-B2 | PEGylated lipids and their use for drug delivery | ALNYLAM PHARMACEUTICALS, INC. (US) | 2018-06-19 | — | — | US | disclosed |
| EP-3202760-A1 | PEGYLATED LIPIDS AND THEIR USE FOR DRUG DELIVERY | Alnylam Pharmaceuticals, Inc. (US) | 2017-08-09 | — | — | EP | disclosed |
| EP-2663548-B1 | PEGYLATED LIPIDS AND THEIR USE FOR DRUG DELIVERY | ALNYLAM PHARMACEUTICALS INC (US) | 2017-04-05 | — | — | EP | disclosed |