Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEC | P42680 | 5/20 | 0.62 |
| ▸ | ITK | Q08881 | 8/20 | 0.48 |
| ▸ | TXK | P42681 | 4/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | IRAK1 | P51617 | 4/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.41 |
| ▸ | MAP3K7 | O43318 | 3/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18688111 | 0.90 | TEC (0.58) | TECITKTXKEGFRIRAK1 | |
| SCHEMBL18687394 | 0.85 | ITK (0.47) | TECITKTXKEGFRIRAK1 | |
| SCHEMBL18687505 | 0.85 | TXK (0.52) | TECITKTXKEGFRIRAK1 | |
| SCHEMBL18687380 | 0.84 | TEC (0.75) | TECITKTXKEGFRIRAK1 | |
| SCHEMBL16767958 | 0.84 | EGFR (0.61) | TECITKTXKEGFRIRAK1 | |
| SCHEMBL18687502 | 0.82 | TEC (0.65) | TECITKTXKBTK | |
| SCHEMBL18688110 | 0.82 | TEC (0.54) | TECITKTXKIRAK1IRAK4 | |
| SCHEMBL18687296 | 0.81 | ACSS2 (0.42) | TECITKTXK | |
| SCHEMBL16767967 | 0.78 | EGFR (0.61) | TECITKTXKEGFRIRAK1 | |
| SCHEMBL18687386 | 0.76 | TEC (1.00) | TECITKTXKEGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017049401-A1 | NEW BENZIMIDAZOLES DERIVATIVES AS TEC KINASES FAMILY INHIBITORS | PHARMASCIENCE INC. (CA) | 2017-03-30 | — | — | WO | disclosed |