SCHEMBL18688232

SCHEMBL18688232

Clc1nc(-c2cc3ccccc3c3ccccc23)c2ncccc2n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 3/20 0.46
CCR8 P51685 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
ALDH1A1 P00352 6/20 0.45
CYP11B1 P15538 1/20 0.41
TOP1 P11387 2/20 0.40
KDM4E B2RXH2 4/20 0.39
CYP3A4 P08684 4/20 0.39
LMNA P02545 5/20 0.38
MAPT P10636 5/20 0.38
PMP22 Q01453 2/20 0.38
TP53 P04637 2/20 0.38
HSP90AA1 P07900 2/20 0.38
MMP9 P14780 2/20 0.38
ALOX15 P16050 2/20 0.38
HTT P42858 2/20 0.38
MMP13 P45452 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
GMNN O75496 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15860244 0.84 CCR1 (0.44) CCR1CCR8L3MBTL1ALDH1A1TOP1
SCHEMBL15860243 0.82 KDM4E (0.53) L3MBTL1ALDH1A1CYP11B1KDM4ELMNA
SCHEMBL30731308 0.82 KDM4E (0.53) L3MBTL1ALDH1A1CYP11B1KDM4ELMNA
SCHEMBL17508362 0.81 CCR1 (0.41) CCR1CCR8L3MBTL1ALDH1A1CYP11B1
SCHEMBL17508370 0.79 CYP11B1 (0.43) CCR1CCR8L3MBTL1ALDH1A1CYP11B1
SCHEMBL24030118 0.75 CCR1 (0.55) CCR1CCR8L3MBTL1ALDH1A1CYP11B1
SCHEMBL31549512 0.75 CCR1 (0.55) CCR1CCR8L3MBTL1ALDH1A1CYP11B1
SCHEMBL31549511 0.75 CCR1 (0.55) CCR1CCR8L3MBTL1ALDH1A1CYP11B1
SCHEMBL24030250 0.75 CCR1 (0.55) CCR1CCR8L3MBTL1ALDH1A1CYP11B1
SCHEMBL15860240 0.75 NPC1 (0.41) CCR1CCR8L3MBTL1ALDH1A1CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10840457-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2020-11-17 US disclosed
WO-2017052099-A1 COMPOUND FOR ORGANIC ELECTRONIC DEVICE, ORGANIC ELECTRONIC DEVICE USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2017-03-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10840457-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof PIEZO1, OR10J3, OCIAD1 CCR1 1993/4885CCR8 2660/4885L3MBTL1 1096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.