Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | CCR8 | P51685 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17508362 | 0.84 | CCR1 (0.41) | CYP11B1CCR1CCR8L3MBTL1ALDH1A1 | |
| SCHEMBL15860241 | 0.83 | ALDH1A1 (0.49) | CCR1CCR8L3MBTL1ALDH1A1RPS6KA5 | |
| SCHEMBL18688232 | 0.79 | CCR1 (0.46) | CYP11B1CCR1CCR8L3MBTL1ALDH1A1 | |
| SCHEMBL15860269 | 0.78 | HTR2B (0.44) | CYP11B1CCR1CCR8L3MBTL1ALDH1A1 | |
| SCHEMBL30731308 | 0.78 | KDM4E (0.53) | CYP11B1L3MBTL1ALDH1A1MAPTMAPK1 | |
| SCHEMBL15860243 | 0.78 | KDM4E (0.53) | CYP11B1L3MBTL1ALDH1A1MAPTMAPK1 | |
| SCHEMBL4146794 | 0.78 | KDM4E (0.52) | L3MBTL1ALDH1A1RPS6KA5MAPTLMNA | |
| SCHEMBL24010021 | 0.75 | IDO1 (0.41) | CCR1CCR8L3MBTL1RPS6KA5IDO1 | |
| SCHEMBL30160518 | 0.75 | IDO1 (0.41) | CCR1CCR8L3MBTL1RPS6KA5IDO1 | |
| SCHEMBL20256139 | 0.75 | RPS6KA5 (0.36) | ALDH1A1RPS6KA5MAPTLMNANISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676767-B2 | Indoloacridine-containing derivative, preparation process and use thereof, and organic luminescent device | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2017-06-13 | — | — | US | disclosed |
| US-20160046621-A1 | INDOLOACRIDINE-CONTAINING DERIVATIVE, PREPARATION PROCESS AND USE THEREOF, AND ORGANIC LUMINESCENT DEVICE | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2016-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160046621-A1 | INDOLOACRIDINE-CONTAINING DERIVATIVE, PREPARATION PROCESS AND USE THEREOF, AND ORGANIC LUMINESCENT DEVICE | AHR, CDYL, SLC18A1 | CYP11B1 2073/4885CCR1 4109/4885CCR8 3753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.