Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29759333 | 0.83 | ALDH1A1 (0.42) | GAAMAPTCA1CA2CA9 | |
| SCHEMBL4663299 | 0.83 | ALDH1A1 (0.42) | GAAMAPTCA1CA2CA9 | |
| SCHEMBL4596400 | 0.81 | TDP1 (0.34) | GAAMEN1HTTKMT2AHTR6 | |
| SCHEMBL25292365 | 0.81 | GAA (0.40) | GAAMAPTCA1CA2CA9 | |
| SCHEMBL31206751 | 0.77 | CYP3A4 (0.37) | GAAMAPTMEN1HTTKMT2A | |
| SCHEMBL25402470 | 0.77 | KHK (0.36) | CA1CA2CA9MEN1HTT | |
| SCHEMBL3208148 | 0.77 | CYP3A4 (0.37) | GAAMAPTMEN1HTTKMT2A | |
| SCHEMBL25402756 | 0.73 | MAPT (0.46) | GAAMAPT | |
| SCHEMBL1866489 | 0.73 | NT5E (0.41) | GAAMAPTCA1CA2CA9 | |
| SCHEMBL25404179 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011057148-A1 | COMPOUNDS AND COMPOSITIONS AS TLR-7 ACTIVITY MODULATORS | IRM LLC (BM) | 2011-05-12 | — | — | WO | disclosed |