Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CD44 | P16070 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3208148 | 1.00 | CYP3A4 (0.37) | CYP3A4ALDH1A1TSHRTP53TDP1 | |
| SCHEMBL29759333 | 0.79 | ALDH1A1 (0.42) | CYP3A4ALDH1A1TP53TDP1POLB | |
| SCHEMBL4663299 | 0.79 | ALDH1A1 (0.42) | CYP3A4ALDH1A1TP53TDP1POLB | |
| SCHEMBL5746102 | 0.77 | ALDH1A1 (0.40) | CYP3A4ALDH1A1TSHRTP53TDP1 | |
| SCHEMBL30421541 | 0.77 | ALDH1A1 (0.40) | CYP3A4ALDH1A1TSHRTP53TDP1 | |
| SCHEMBL1868968 | 0.77 | GAA (0.40) | TDP1MEN1HTTKMT2AGAA | |
| SCHEMBL3886713 | 0.77 | POLB (0.53) | CYP3A4ALDH1A1TSHRTP53TDP1 | |
| SCHEMBL11985860 | 0.77 | ALDH1A1 (0.32) | ALDH1A1POLBMAPK1SMN1; SMN2 | |
| SCHEMBL29513014 | 0.77 | POLB (0.53) | CYP3A4ALDH1A1TSHRTP53TDP1 | |
| SCHEMBL4596400 | 0.77 | TDP1 (0.34) | TDP1MEN1HTTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705308-A1 | EGFR INHIBITORS FOR TREATING DISEASE | Blossomhill Therapeutics, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024229087-A1 | EGFR INHIBITORS FOR TREATING DISEASE | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2024-11-07 | — | — | WO | disclosed |
| WO-2024229091-A1 | EGFR INHIBITORS FOR TREATING DISEASE | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2024-11-07 | — | — | WO | disclosed |