Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1887812 | 0.81 | ADORA2B (0.39) | ADORA2AADORA1 | |
| SCHEMBL1869565 | 0.80 | ADORA2A (0.40) | ADORA2AADORA1 | |
| SCHEMBL1883341 | 0.67 | ADORA1 (0.46) | ADORA2AADORA1 | |
| SCHEMBL1867015 | 0.65 | ADORA1 (0.47) | ADORA2AADORA1 | |
| SCHEMBL1867769 | 0.64 | MAOA (0.38) | ADORA2AADORA1 | |
| SCHEMBL1868403 | 0.64 | ADORA2B (0.35) | ADORA2AADORA1 | |
| SCHEMBL1875998 | 0.63 | ADORA1 (0.38) | ADORA2AADORA1 | |
| SCHEMBL1865499 | 0.62 | ADORA1 (0.36) | ADORA2AADORA1 | |
| SCHEMBL1867846 | 0.62 | ADORA1 (0.41) | ADORA2AADORA1 | |
| SCHEMBL1869359 | 0.62 | CYP2C9 (0.34) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2499142-A1 | SUBSTITUTED FUSED PYRIMIDINE COMPOUNDS, ITS PREPARATION AND USES THEREOF | Advinus Therapeutics Limited (IN) | 2012-09-19 | — | — | EP | disclosed |
| WO-2011055391-A1 | SUBSTITUTED FUSED PYRIMIDINE COMPOUNDS, ITS PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-05-12 | — | — | WO | disclosed |