SCHEMBL18692007

SCHEMBL18692007

C[Si](C)(O)c1occ2ccccc12

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.33
ALDH1A1 P00352 4/20 0.33
HSD17B10 Q99714 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
TSHR P16473 2/20 0.33
ENPP3 O14638 1/20 0.33
ENPP1 P22413 1/20 0.33
CYP1A2 P05177 3/20 0.32
CCR4 P51679 1/20 0.32
CYP2C19 P33261 1/20 0.31
HPRT1 P00492 1/20 0.31
PARP1 P09874 1/20 0.31
PRKCI P41743 1/20 0.31
PDE4B Q07343 1/20 0.31
PTPN22 Q9Y2R2 1/20 0.30
TRPM4 Q8TD43 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3128190 0.83 CYP2A6 (0.36) CYP2A6ALDH1A1HSD17B10TDP1TSHR
SCHEMBL1097671 0.69 CYP2A6 (0.42) CYP2A6ALDH1A1HSD17B10TDP1TSHR
SCHEMBL276957 0.69 CYP1A2 (0.42) CYP2A6ALDH1A1HSD17B10TDP1TSHR
SCHEMBL28306537 0.67 CYP1A2 (0.41) CYP2A6ALDH1A1HSD17B10TDP1TSHR
SCHEMBL112635 0.65 MAPT (0.42) ALDH1A1HSD17B10TSHRCYP1A2CYP2C19
SCHEMBL2961435 0.65 UGT2B7 (0.38) CYP2A6ALDH1A1HSD17B10TDP1TSHR
SCHEMBL5143294 0.65 CYP2A6 (0.44) CYP2A6ALDH1A1HSD17B10TDP1TSHR
SCHEMBL31158054 0.65 CYP2A6 (0.44) CYP2A6ALDH1A1HSD17B10TDP1TSHR
SCHEMBL27610645 0.64 ACP3 (0.34) CYP2A6ALDH1A1HSD17B10TDP1TSHR
SCHEMBL1605255 0.64 ALDH1A1 (0.39) CYP2A6ALDH1A1HSD17B10TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10723845-B2 Process for preparing linear carbosiloxane polymers DOW SILICONES CORPORATION (US) 2020-07-28 US disclosed
US-20200079911-A1 PROCESS FOR PREPARING LINEAR CARBOSILOXANE POLYMERS DOW CORNING EUROPE S.A. 2020-03-12 US disclosed
EP-3153540-B1 PROCESS FOR PREPARING LINEAR CARBOSILOXANE POLYMERS DOW CORNING (US) 2018-06-06 EP disclosed
WO-2017062091-A1 PROCESS FOR PREPARING LINEAR CARBOSILOXANE POLYMERS DOW CORNING CORPORATION (US) 2017-04-13 WO disclosed
EP-3153540-A1 PROCESS FOR PREPARING LINEAR CARBOSILOXANE POLYMERS Dow Corning Corporation (US) 2017-04-12 EP disclosed