Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.39 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28471616 | 0.70 | ALDH1A1 (0.39) | CYP1A2PTPN22TRPM4HSD17B10ALDH1A1 | |
| SCHEMBL1097671 | 0.70 | CYP2A6 (0.42) | CYP1A2HSD17B10ALDH1A1CYP2A6TSHR | |
| SCHEMBL276956 | 0.70 | ALDH1A1 (0.39) | CYP1A2HSD17B10ALDH1A1CYP2A6TSHR | |
| SCHEMBL1605255 | 0.70 | ALDH1A1 (0.39) | CYP1A2PTPN22HSD17B10ALDH1A1CYP2A6 | |
| SCHEMBL2008998 | 0.70 | ALDH1A1 (0.42) | CYP1A2HSD17B10ALDH1A1CYP2A6TSHR | |
| SCHEMBL4079696 | 0.70 | CYP2A6 (0.42) | CYP1A2HSD17B10ALDH1A1CYP2A6TSHR | |
| SCHEMBL4897405 | 0.70 | ALDH1A1 (0.39) | CYP1A2PTPN22TRPM4HSD17B10ALDH1A1 | |
| SCHEMBL286416 | 0.70 | ALDH1A1 (0.39) | CYP1A2TRPM4HSD17B10ALDH1A1CYP2A6 | |
| SCHEMBL21179481 | 0.70 | ALDH1A1 (0.39) | CYP1A2PTPN22HSD17B10ALDH1A1CYP2A6 | |
| SCHEMBL2012336 | 0.70 | ALDH1A1 (0.39) | CYP1A2PTPN22TRPM4HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0420570-A2 | Trans 2,3-disubstituted-2,3-dihydro-5-hydroxy-benzofurans as inhibitors of leukotriene biosynthesis | MERCK & CO. INC. (US) | 1991-04-03 | — | — | EP | claimed |
| CN-119192108-B | Preparation method of chiral phthaloyl ester prodrug | 贵州大学 | 2026-05-01 | — | — | CN | disclosed |
| CN-119192108-A | Preparation method of chiral phthaloyl ester prodrug | 贵州大学 | 2024-12-27 | — | — | CN | disclosed |
| EP-4479054-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | Nico Therapeutics, Inc. (US) | 2024-12-25 | — | — | EP | disclosed |
| CN-118373791-A | Allyl phthalide compound and preparation method and application thereof | 南京工业大学 | 2024-07-23 | — | — | CN | disclosed |
| CN-118373791-A | Allyl phthalide compound and preparation method and application thereof | 南京工业大学 | 2024-07-23 | — | — | CN | disclosed |
| CN-117800924-A | Synthesis method of PARP inhibitor intermediate | 南京江原安迪科正电子研究发展有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-114950505-B | Catalyst for preparing beta-phenethyl alcohol by hydrogenation of styrene oxide, and preparation method and application thereof | 浙江大学 | 2023-11-24 | — | — | CN | disclosed |
| WO-2023158708-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | DENALI THERAPEUTICS INC. (US) | 2023-08-24 | — | — | WO | disclosed |
| US-11174272-B2 | 1-arylcarbonyl-4-oxy-piperidine compounds useful for the treatment of neurodegenerative diseases | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-11-16 | — | — | US | disclosed |
| US-4341793-A | HYPOGLYCEMIC AGENTS AND DIETETICS | BEECHAM GROUP LIMITED (GB) | 1982-07-27 | — | — | US | disclosed |
| US-4301292-A | 1-[2-(4,5-Dihydro-4,4-dialkyl-2-oxazolyl)phenyl]-4-(dialkylamino)cyclohexanol | HOECHST-ROUSSEL PHARMACEUTICALS, INCORPORATED (US) | 1981-11-17 | — | — | US | disclosed |
| US-4292243-A | 3\"-Phenyldispiro[1,3-dioxolane-2,4'-cyclohexane-1',1\"-(3\"H)-isobenzofuran] | HOECHST ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1981-09-29 | — | — | US | disclosed |
| US-4292245-A | 3'-Phenylspiro[cyclohexane-1,1'(3'H)-isobenzofuran]-4-one | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1981-09-29 | — | — | US | disclosed |
| US-4290958-A | Spiro[cyclohexane-1,1'(3'H)-isobenzofuran]s | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1981-09-22 | — | — | US | disclosed |
| US-4288623-A | 1-Aryl-4-amino-cyclohexan-1-ols | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1981-09-08 | — | — | US | disclosed |
| EP-0029320-A2 | Secondary ethanol amines, their preparation and their use in pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1981-05-27 | — | — | EP | disclosed |
| EP-0027522-A1 | Spiro(cyclohexane-1,1'(3'H)-isobenzofuran)s, processes and intermediates for their preparation and pharmaceutical compositions containing them | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1981-04-29 | — | — | EP | disclosed |
| US-4263317-A | Spiro[cyclohexane-1,1'(3'H)-isobenzofuran]s | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1981-04-21 | — | — | US | disclosed |
| US-4032656-A | ANTIPROSTAGLANDIN ACTIVITY, ANTIDIARRHEA AGENTS | SMITHKLINE CORPORATION (US) | 1977-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11174272-B2 | 1-arylcarbonyl-4-oxy-piperidine compounds useful for the treatment of neurodegenerative diseases | SNCA, HTT, PSEN1 | CYP1A2 3436/4885PTPN22 2021/4885TRPM4 1526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.