Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | MASP2 | O00187 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.35 |
| ▸ | CTSS | P25774 | 3/20 | 0.34 |
| ▸ | CTSK | P43235 | 3/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 4/20 | 0.33 |
| ▸ | PGA5 | P0DJD9 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | KLK1 | P06870 | 1/20 | 0.33 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.33 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.33 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1869265 | 1.00 | MME (0.38) | MMEACECPA1ACE2MASP2 | |
| SCHEMBL1869264 | 1.00 | MME (0.38) | MMEACECPA1ACE2MASP2 | |
| SCHEMBL1868416 | 0.89 | MASP2 (0.41) | MMEACECPA1ACE2MASP2 | |
| SCHEMBL1864424 | 0.84 | CTSS (0.48) | MASP2CTSSCTSKCTSBPTPN1 | |
| SCHEMBL1867510 | 0.82 | MASP2 (0.41) | MMEACECPA1ACE2MASP2 | |
| SCHEMBL1873380 | 0.82 | MASP2 (0.43) | MMEACECPA1ACE2MASP2 | |
| SCHEMBL1873386 | 0.82 | MASP2 (0.43) | MMEACECPA1ACE2MASP2 | |
| Hydrochloric Acid SCHEMBL1869464 | 0.81 | MASP2 (0.41) | MMEACECPA1ACE2MASP2 | |
| SCHEMBL1871675 | 0.81 | MASP2 (0.42) | MMEACECPA1ACE2MASP2 | |
| SCHEMBL1871667 | 0.81 | MASP2 (0.42) | MMEACECPA1ACE2MASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051672-A1 | AZAINDOLE DERIVATIVES | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | disclosed |