Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1871181 | 0.91 | MASP2 (0.43) | MASP2KLKB1CHRNA7METAP2ALDH1A1 | |
| SCHEMBL1874196 | 0.91 | MASP2 (0.43) | MASP2KLKB1CHRNA7METAP2ALDH1A1 | |
| SCHEMBL1860917 | 0.89 | MASP2 (0.44) | MASP2KLKB1CHRNA7METAP2ALDH1A1 | |
| SCHEMBL1867433 | 0.89 | MASP2 (0.42) | MASP2KLKB1CHRNA7METAP2ALDH1A1 | |
| SCHEMBL1869822 | 0.87 | MASP2 (0.43) | MASP2KLKB1CHRNA7METAP2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL1873249 | 0.87 | DPP4 (0.43) | MASP2KLKB1CHRNA7TACR1MEN1 | |
| SCHEMBL1867033 | 0.85 | MASP2 (0.43) | MASP2KLKB1CHRNA7 | |
| SCHEMBL1432630 | 0.85 | DPP4 (0.39) | MASP2KLKB1ALDH1A1LMNAMEN1 | |
| SCHEMBL1431769 | 0.85 | DPP4 (0.39) | MASP2KLKB1ALDH1A1LMNAMEN1 | |
| SCHEMBL1870902 | 0.84 | MASP2 (0.43) | MASP2KLKB1CHRNA7METAP2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051672-A1 | AZAINDOLE DERIVATIVES | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | claimed |
| WO-2011051672-A1 | AZAINDOLE DERIVATIVES | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | disclosed |