Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 2/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 6/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | MC5R | P33032 | 1/20 | 0.39 |
| ▸ | MC3R | P41968 | 1/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.38 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.38 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1871181 | 0.93 | MASP2 (0.43) | MASP2MEN1KMT2AMETAP2KLKB1 | |
| SCHEMBL1874196 | 0.93 | MASP2 (0.43) | MASP2MEN1KMT2AMETAP2KLKB1 | |
| SCHEMBL1875013 | 0.93 | KLKB1 (0.44) | MASP2KLKB1KLK1CHRNA7METTL3 | |
| SCHEMBL1867894 | 0.92 | MASP2 (0.43) | MASP2KLKB1KLK1TACR1METTL3 | |
| SCHEMBL1867150 | 0.92 | MASP2 (0.43) | MASP2KLKB1KLK1TACR1METTL3 | |
| SCHEMBL1880431 | 0.92 | MASP2 (0.44) | MASP2MEN1KMT2AMETAP2KLKB1 | |
| SCHEMBL1867433 | 0.91 | MASP2 (0.42) | MASP2MEN1KMT2AMETAP2KLKB1 | |
| Trifluoroacetic Acid SCHEMBL1873249 | 0.90 | DPP4 (0.43) | MASP2MEN1KMT2AKLKB1TACR1 | |
| SCHEMBL1870064 | 0.89 | MASP2 (0.42) | MASP2KLKB1KLK1TACR1 | |
| SCHEMBL1871442 | 0.88 | MASP2 (0.45) | MASP2KLKB1KLK1TACR1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051672-A1 | AZAINDOLE DERIVATIVES | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | claimed |
| WO-2011051672-A1 | AZAINDOLE DERIVATIVES | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | disclosed |