Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.47 |
| ▸ | RET | P07949 | 2/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CCDC6 | Q16204 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17315063 | 0.99 | KDR (0.47) | KDRNTRK1RETCSF1RKCNH2 | |
| Lithium Ion SCHEMBL17315061 | 0.91 | KDR (0.49) | KDRNTRK1RETCSF1RKCNH2 | |
| SCHEMBL18696058 | 0.90 | KDR (0.55) | KDRNTRK1RETCSF1RKCNH2 | |
| SCHEMBL17315054 | 0.89 | KDR (0.54) | KDRNTRK1RETCSF1RKCNH2 | |
| SCHEMBL18696065 | 0.87 | NTRK1 (0.46) | KDRNTRK1RETCSF1RKCNH2 | |
| SCHEMBL17323692 | 0.86 | GABRA1 (0.48) | KDRNTRK1RETCSF1RKCNH2 | |
| SCHEMBL17315048 | 0.86 | NTRK1 (0.45) | KDRNTRK1RETCSF1RKCNH2 | |
| SCHEMBL17315131 | 0.85 | GABRA1 (0.47) | KDRNTRK1RETCSF1RKCNH2 | |
| SCHEMBL17315064 | 0.85 | FGFR1 (0.54) | KDRNTRK1RETCSF1RKCNH2 | |
| SCHEMBL17323774 | 0.85 | MAP3K8 (0.46) | KDRNTRK1RETCSF1RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074778-B | Benzimidazole analogs and related methods | 代表亚利桑那大学的亚利桑那校董会 | 2019-12-13 | — | — | CN | disclosed |
| US-9988371-B2 | Benzimidazole analogues and related methods | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2018-06-05 | — | — | US | disclosed |
| US-9988371-B2 | Benzimidazole analogues and related methods | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2018-06-05 | — | — | US | disclosed |
| US-20170101401-A1 | BENZIMIDAZOLE ANALOGUES AND RELATED METHODS | THE ARIZONA BOARD OF REGENTS, ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2017-04-13 | — | — | US | disclosed |
| US-20170101401-A1 | BENZIMIDAZOLE ANALOGUES AND RELATED METHODS | THE ARIZONA BOARD OF REGENTS, ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2017-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170101401-A1 | BENZIMIDAZOLE ANALOGUES AND RELATED METHODS | ABL1, BTK, JAK2 | KDR 262/4885NTRK1 441/4885RET 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.