SCHEMBL1869702

SCHEMBL1869702

CO[Si](OC)(OC)C(C)CC=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1725598 0.75
SCHEMBL9815183 0.70
SCHEMBL397678 0.69
SCHEMBL28092568 0.69
SCHEMBL28687749 0.67 TSHR (0.39)
SCHEMBL108610 0.67 TSHR (0.30)
SCHEMBL10715314 0.67
SCHEMBL9815174 0.67 ALDH1A1 (0.33)
SCHEMBL398839 0.65
SCHEMBL983920 0.65 ALDH1A1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9303263-B2 Aptamers that bind CD271 VIVONICS, INC. (US) 2016-04-05 US disclosed
US-20150376619-A1 APTAMERS THAT BIND CD271 VIVONICS, INC. (US) 2015-12-31 US disclosed
US-9085773-B2 Methods for identifying nucleic acid ligands VIVONICS, INC. (US) 2015-07-21 US disclosed
WO-2014134403-A9 APTAMERS THAT BIND CD271 VIVONICS, INC. (US) 2014-12-24 WO disclosed
WO-2014134403-A2 APTAMERS THAT BIND CD271 VIVONICS, INC. (US) 2014-09-04 WO disclosed
US-20130273551-A1 METHODS FOR IDENTIFYING NUCLEIC ACID LIGANDS INFOSCITEX 2013-10-17 US disclosed
US-20130252843-A1 METHOD OF MAKING AND USING FLUORESCENT-TAGGED NANOPARTICLES AND MICROARRAYS THE STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTL (US) 2013-09-26 US disclosed
US-8460899-B2 Methods for identifying nucleic acid ligands VIVONICS, INC. (US) 2013-06-11 US disclosed
US-20120301890-A1 METHODS FOR IDENTIFYING NUCLEIC ACID LIGANDS INFOSCITEX CORPORATION (US) 2012-11-29 US disclosed
US-8236570-B2 Methods for identifying nucleic acid ligands INFOSCITEX (US) 2012-08-07 US disclosed
WO-2012071461-A2 METHOD OF MAKING AND USING FLUORESCENT-TAGGED NANOPARTICLES AND MICROARRAYS THE STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND STATE UNIVERSITY (US) 2012-05-31 WO disclosed
WO-2011056420-A1 METHODS FOR IDENTIFYING NUCLEIC ACID LIGANDS INFOSCITEX CORPORATION (US) 2011-05-12 WO disclosed
US-20110104667-A1 METHODS FOR IDENTIFYING NUCLEIC ACID LIGANDS INFOSCITEX CORPORATION (US) 2011-05-05 US disclosed