⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9815183 | 0.97 | — | — | |
| SCHEMBL14919823 | 0.72 | — | — | |
| SCHEMBL9815174 | 0.70 | ALDH1A1 (0.33) | — | |
| SCHEMBL8463762 | 0.69 | — | — | |
| SCHEMBL7784471 | 0.69 | — | — | |
| SCHEMBL1869702 | 0.69 | — | — | |
| SCHEMBL5189093 | 0.67 | — | — | |
| SCHEMBL16240 | 0.65 | — | — | |
| SCHEMBL1330501 | 0.65 | — | — | |
| SCHEMBL19741477 | 0.65 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104371050-B | The metallocene of sub- cyclobutyl bridging and antigravity system comprising it | 切弗朗菲利浦化学公司 | 2019-02-19 | — | — | CN | disclosed |
| CN-104418963-B | Higher density polyolefin with improved stress cracking resistance | 切弗朗菲利浦化学公司 | 2018-07-10 | — | — | CN | disclosed |
| CN-104292368-B | The method for generating the aluminum oxide activating agent carrier of fluorination-chlorided silica-cladding and the catalyst system containing it | 切弗朗菲利浦化学公司 | 2018-05-22 | — | — | CN | disclosed |
| CN-104004116-B | Dual activator carried catalyst system | 切弗朗菲利浦化学公司 | 2018-03-09 | — | — | CN | disclosed |
| CN-103183700-B | Catalyst compositions for the polymerization of olefins | 切弗朗菲利浦化学公司 | 2017-05-17 | — | — | CN | disclosed |
| CN-105849138-A | Catalyst systems containing boron-bridged cyclopentadienyl-fluorenyl metallocene compounds having alkenyl substituents | 切弗朗菲利浦化学公司 | 2016-08-10 | — | — | CN | disclosed |