Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22984226 | 0.85 | CA12 (0.36) | CA12CA1CA9ALDH1A1LMNA | |
| SCHEMBL24258464 | 0.80 | SMN1; SMN2 (0.43) | ALDH1A1LMNAMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL20443831 | 0.79 | SMN1; SMN2 (0.47) | ALDH1A1LMNAMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL18942380 | 0.79 | KDM4E (0.39) | CA12CA1CA9ALDH1A1LMNA | |
| SCHEMBL21414070 | 0.76 | ALDH1A1 (0.44) | CA12CA1CA9ALDH1A1LMNA | |
| SCHEMBL23597064 | 0.74 | SMN1; SMN2 (0.33) | CA12CA1CA9ALDH1A1LMNA | |
| SCHEMBL22984233 | 0.74 | SMN1; SMN2 (0.61) | ALDH1A1LMNAMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL20735351 | 0.72 | SMN1; SMN2 (0.49) | ALDH1A1LMNAMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL18697325 | 0.71 | SMN1; SMN2 (0.39) | ALDH1A1LMNAMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL20419957 | 0.71 | RAB9A (0.54) | ALDH1A1LMNAMAPK1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210292463-A1 | DYNAMIC POLYURETHANE NETWORKS WITH POST-RECYCLING RETENTION OF CROSS-LINKING DENSITIES AND MECHANICAL PROPERTIES | NORTHWESTERN UNIVERSITY | 2021-09-23 | — | — | US | disclosed |
| EP-2791196-B1 | HYBRID POLYMERS | SOLVAY SPECIALTY POLYMERS IT (IT) | 2017-04-05 | — | — | EP | disclosed |