SCHEMBL18697905 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	ALDH1A1	P00352	1/20	0.38

▸	RIPK1	Q13546	3/20	0.36

▸	TNK2	Q07912	2/20	0.34

▸	HSPA2	P54652	1/20	0.34

▸	ABCB1	P08183	1/20	0.33

▸	SLC22A1	O15245	1/20	0.33

▸	LMNA	P02545	1/20	0.33

▸	PRMT5	O14744	1/20	0.33

▸	WDR77	Q9BQA1	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25914985	1.00	ALDH1A1 (0.38)	ALDH1A1RIPK1TNK2HSPA2ABCB1
SCHEMBL14996153	0.91	ALDH1A1 (0.36)	ALDH1A1RIPK1TNK2
SCHEMBL24791260	0.91	ALDH1A1 (0.36)	ALDH1A1RIPK1TNK2
SCHEMBL881372	0.91	ALDH1A1 (0.36)	ALDH1A1RIPK1TNK2
SCHEMBL24168927	0.89	ALDH1A1 (0.35)	ALDH1A1RIPK1TNK2SLC22A1
SCHEMBL10187389	0.84	NPC1 (0.39)	ALDH1A1RIPK1TNK2
SCHEMBL17617320	0.84	ALDH1A1 (0.36)	ALDH1A1RIPK1TNK2
SCHEMBL12398186	0.84	RIPK1 (0.35)	RIPK1TNK2
SCHEMBL15084410	0.84	RIPK1 (0.35)	RIPK1TNK2
SCHEMBL10171966	0.83	ALDH1A1 (0.36)	ALDH1A1RIPK1TNK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3150608-A1	2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT	Gilead Sciences, Inc. (US)	2017-04-05	—	—	EP	disclosed