Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 16/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14134297 | 0.86 | POLB (0.34) | QPCTPOLBGAAKMT2AHSD11B1 | |
| SCHEMBL14148472 | 0.83 | QPCT (0.51) | QPCTHSD11B1 | |
| SCHEMBL12273935 | 0.77 | QPCT (0.49) | QPCT | |
| SCHEMBL2381919 | 0.77 | QPCT (0.52) | QPCT | |
| SCHEMBL4300306 | 0.74 | ALDH1A1 (0.53) | QPCTPOLBGAAKMT2A | |
| SCHEMBL4305666 | 0.73 | QPCT (0.55) | QPCT | |
| Hydrochloric Acid SCHEMBL2382192 | 0.73 | QPCT (0.54) | QPCT | |
| SCHEMBL14148277 | 0.73 | QPCT (0.54) | QPCT | |
| SCHEMBL14148282 | 0.73 | QPCT (0.54) | QPCT | |
| SCHEMBL2381935 | 0.71 | QPCT (0.50) | QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9610368-B2 | Radiolabelled glutaminyl cyclase (QC) inhibitors and uses of same | PROBIODRUG AG (DE) | 2017-04-04 | — | — | US | disclosed |