Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 17/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18698224 | 0.83 | QPCT (0.43) | QPCTHSD11B1 | |
| SCHEMBL13662446 | 0.77 | QPCT (0.50) | QPCT | |
| SCHEMBL4305666 | 0.77 | QPCT (0.55) | QPCT | |
| SCHEMBL14148277 | 0.77 | QPCT (0.54) | QPCT | |
| SCHEMBL14148282 | 0.77 | QPCT (0.54) | QPCT | |
| Hydrochloric Acid SCHEMBL2382192 | 0.77 | QPCT (0.54) | QPCT | |
| SCHEMBL4300306 | 0.76 | ALDH1A1 (0.53) | QPCT | |
| SCHEMBL12274289 | 0.76 | QPCT (0.85) | QPCT | |
| SCHEMBL2381919 | 0.75 | QPCT (0.52) | QPCT | |
| SCHEMBL12274578 | 0.75 | QPCT (0.56) | QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120301398-A1 | RADIOLABELLED GLUTAMINYL CYCLASE (QC) INHIBITORS AND USES OF SAME | PROBIODRUG AG (DE) | 2012-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120301398-A1 | RADIOLABELLED GLUTAMINYL CYCLASE (QC) INHIBITORS AND USES OF SAME | QPCT, GLUL, GLS | QPCT 1/4885HSD11B1 3535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.