Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 19/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18699937 | 0.85 | CCR2 (0.71) | CCR2CYP3A4 | |
| SCHEMBL18699939 | 0.85 | CCR2 (0.71) | CCR2CYP3A4 | |
| SCHEMBL19337949 | 0.85 | CCR2 (0.63) | CCR2KCNH2 | |
| SCHEMBL14100727 | 0.85 | CCR2 (0.63) | CCR2KCNH2 | |
| SCHEMBL12528261 | 0.81 | CCR2 (0.50) | CCR2KCNH2 | |
| SCHEMBL26060586 | 0.81 | CCR2 (0.50) | CCR2KCNH2 | |
| SCHEMBL26061234 | 0.81 | CCR2 (0.50) | CCR2KCNH2 | |
| SCHEMBL15325952 | 0.80 | CCR2 (1.00) | CCR2KCNH2 | |
| SCHEMBL14636914 | 0.80 | CCR2 (1.00) | CCR2KCNH2CYP3A4 | |
| SCHEMBL13226327 | 0.79 | CCR2 (0.77) | CCR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2834234-B1 | FUSED CYCLOPENTYL ANTAGONISTS OF CCR2 | JANSSEN PHARMACEUTICA NV (BE) | 2017-09-13 | — | — | EP | disclosed |
| EP-2875023-B1 | OCTAHYDRO-CYCLOPENTAPYRROLYL ANTAGONISTS OF CCR2 | JANSSEN PHARMACEUTICA NV (BE) | 2017-04-05 | — | — | EP | disclosed |