Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 5/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2234667 | 0.78 | — | — | |
| SCHEMBL29053129 | 0.74 | CA12 (0.33) | TRPA1TDP1NPSR1 | |
| SCHEMBL3830377 | 0.73 | — | — | |
| SCHEMBL28281750 | 0.72 | CHRM3 (0.38) | TDP1NPSR1 | |
| SCHEMBL12726718 | 0.70 | NPSR1 (0.35) | TDP1NPSR1 | |
| SCHEMBL30850107 | 0.68 | CHRM3 (0.33) | NPSR1 | |
| SCHEMBL30104119 | 0.65 | TSHR (0.33) | TRPA1TDP1 | |
| SCHEMBL30564905 | 0.62 | NPSR1 (0.34) | TRPA1NPSR1 | |
| SCHEMBL12726713 | 0.60 | KMT2A (0.36) | — | |
| SCHEMBL6616930 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227068-B | GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2023-06-13 | — | — | CN | disclosed |
| EP-2493871-A1 | NOVEL OXIME DERIVATIVES AND THEIR USE AS ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | Domain Therapeutics (FR) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011051478-A1 | NOVEL OXIME DERIVATIVES AND THEIR USE AS ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | DOMAIN THERAPEUTICS (FR) | 2011-05-05 | — | — | WO | disclosed |