Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1759161 | 0.80 | — | — | |
| SCHEMBL29053129 | 0.74 | CA12 (0.33) | CHRM3LMNACHRM2CHRM4CHRM5 | |
| SCHEMBL1895595 | 0.73 | CHRM3 (0.32) | CHRM3LMNACHRM2CHRM4CHRM5 | |
| SCHEMBL30051946 | 0.71 | CHRM3 (0.33) | CHRM3LMNACHRM2CHRM4CHRM5 | |
| SCHEMBL30731288 | 0.69 | CA12 (0.32) | CHRM3LMNACHRM2CHRM4CHRM5 | |
| SCHEMBL3664888 | 0.68 | CA12 (0.35) | CHRM3LMNACHRM2CHRM4CHRM5 | |
| SCHEMBL1870026 | 0.68 | TRPA1 (0.31) | NPSR1 | |
| SCHEMBL18104379 | 0.65 | MAPK1 (0.41) | MAPK1 | |
| SCHEMBL23280497 | 0.63 | CHRM3 (0.37) | CHRM3LMNACHRM2CHRM4CHRM5 | |
| SCHEMBL21277825 | 0.60 | LOXL2 (0.40) | CHRM3LMNACHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551862-B | Macrocyclic inhibitors of peptidyl arginine deiminase | 吉利德科学公司 | 2024-04-12 | — | — | CN | disclosed |