Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CFTR | P13569 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30104125 | 0.83 | POLB (0.33) | — | |
| SCHEMBL28915908 | 0.69 | GAA (0.31) | GAATRPA1 | |
| SCHEMBL28281750 | 0.66 | CHRM3 (0.38) | TSHRLMNAALDH1A1TDP1 | |
| SCHEMBL1870026 | 0.65 | TRPA1 (0.31) | TRPA1TDP1 | |
| SCHEMBL12726718 | 0.65 | NPSR1 (0.35) | TSHRMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL3830377 | 0.64 | — | — | |
| SCHEMBL11291314 | 0.62 | SLC6A3 (0.39) | TSHRSLC6A3SLC6A2SLC6A4 | |
| SCHEMBL19690478 | 0.61 | TRPA1 (0.51) | TSHRSMN1; SMN2LMNATRPA1ALDH1A1 | |
| SCHEMBL29690715 | 0.60 | — | — | |
| SCHEMBL11182132 | 0.57 | NPSR1 (0.38) | TSHRSMN1; SMN2LMNAGAATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115353546-B | Preparation and application of oligopeptide modified bisindolylethyl-beta-carboline-3-carboxylic acid | 首都医科大学 | 2024-10-08 | — | — | CN | disclosed |
| CN-115353546-A | Preparation and application of oligopeptide-modified bis-indolylethyl-beta-carboline-3-carboxylic acid | 首都医科大学 | 2022-11-18 | — | — | CN | disclosed |