SCHEMBL18700402

SCHEMBL18700402

CC1(C)c2ccccc2N(c2cc(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)cc(N3c4ccccc4C(C)(C)c4ccc5c(oc6ccccc65)c43)c2)c2c1ccc1c2oc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.35
MAPT P10636 7/20 0.32
ALDH1A1 P00352 5/20 0.32
LMNA P02545 4/20 0.32
HSD17B10 Q99714 2/20 0.32
POLB P06746 2/20 0.32
KMT2A Q03164 2/20 0.32
USP2 O75604 1/20 0.32
HTT P42858 1/20 0.32
KDM4E B2RXH2 3/20 0.32
MAPK1 P28482 1/20 0.32
HPGD P15428 1/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22969905 0.93 TSHR (0.35) TSHRMAPTALDH1A1LMNAHSD17B10
SCHEMBL18700406 0.92 TSHR (0.36) TSHRMAPTALDH1A1LMNAHSD17B10
SCHEMBL22969876 0.88 TSHR (0.32) TSHRMAPTALDH1A1LMNAKMT2A
SCHEMBL22969678 0.84 MEN1 (0.30) KMT2AMEN1
SCHEMBL18700405 0.83 MEN1 (0.33) KMT2AKDM4EMEN1NPSR1
SCHEMBL13231651 0.79 L3MBTL1 (0.40) TSHRMAPTALDH1A1LMNAHSD17B10
SCHEMBL15759680 0.79 HSP90AA1 (0.32) MAPTALDH1A1KMT2AKDM4EHPGD
SCHEMBL15804139 0.79 KMT2A (0.41) MAPTALDH1A1LMNAPOLBKMT2A
SCHEMBL17278561 0.78 ALOX5 (0.40) TSHRMAPTALDH1A1LMNAHSD17B10
SCHEMBL17278555 0.78 ALOX5 (0.37) TSHRMAPTALDH1A1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9882147-B2 Delayed fluorescence material and organic light emitting device having the delayed fluorescence material Research & Business Foundation Sungkyunkwan University (KR) 2018-01-30 US disclosed
US-9882147-B2 Delayed fluorescence material and organic light emitting device having the delayed fluorescence material Research & Business Foundation Sungkyunkwan University (KR) 2018-01-30 US disclosed
US-20170098779-A1 DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT EMITTING DEVICE HAVING THE DELAYED FLUORESCENCE MATERIAL Research & Business Foundation Sungkyunkwan University (KR) 2017-04-06 US disclosed
US-20170098779-A1 DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT EMITTING DEVICE HAVING THE DELAYED FLUORESCENCE MATERIAL Research & Business Foundation Sungkyunkwan University (KR) 2017-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170098779-A1 DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT EMITTING DEVICE HAVING THE DELAYED FLUORESCENCE MATERIAL HNRNPD, HNRNPDL, HNRNPF TSHR 4761/4885MAPT 1720/4885ALDH1A1 314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.