SCHEMBL18700403

SCHEMBL18700403

CN1c2ccccc2C(C)(C)c2ccc3c(oc4ccccc43)c21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.46
NPSR1 Q6W5P4 2/20 0.46
KMT2A Q03164 10/20 0.39
MEN1 O00255 9/20 0.39
CYP2C19 P33261 2/20 0.39
PGR P06401 1/20 0.39
HTT P42858 6/20 0.39
LMNA P02545 5/20 0.39
MAPT P10636 10/20 0.37
POLB P06746 2/20 0.36
GAA P10253 3/20 0.36
THRB P10828 3/20 0.36
RECQL P46063 3/20 0.36
GLA P06280 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP2D6 P10635 2/20 0.35
CYP1A2 P05177 1/20 0.35
TSHR P16473 3/20 0.35
ALDH1A1 P00352 3/20 0.35
MAPK1 P28482 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15804139 0.87 KMT2A (0.41) KDM4ENPSR1KMT2AMEN1CYP2C19
SCHEMBL18700405 0.81 MEN1 (0.33) KDM4ENPSR1KMT2AMEN1CYP2C19
SCHEMBL18700409 0.80 MEN1 (0.32) KDM4ENPSR1KMT2AMEN1CYP2C19
SCHEMBL15759679 0.79 ALOX5 (0.41) KDM4ENPSR1KMT2AMEN1CYP2C19
SCHEMBL17171629 0.79 KMT2A (0.39) KDM4ENPSR1KMT2AMEN1CYP2C19
SCHEMBL15759680 0.78 HSP90AA1 (0.32) KDM4ENPSR1KMT2AMEN1CYP2C19
SCHEMBL12282655 0.78 KMT2A (0.38) KDM4ENPSR1KMT2AMEN1CYP2C19
SCHEMBL23920103 0.77 MEN1 (0.33) KDM4ENPSR1KMT2AMEN1CYP2C19
SCHEMBL21945882 0.77 PGR (0.33) KDM4ENPSR1KMT2AMEN1CYP2C19
SCHEMBL18700406 0.77 TSHR (0.36) KDM4ENPSR1KMT2AMEN1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9882147-B2 Delayed fluorescence material and organic light emitting device having the delayed fluorescence material Research & Business Foundation Sungkyunkwan University (KR) 2018-01-30 US disclosed
US-20170098779-A1 DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT EMITTING DEVICE HAVING THE DELAYED FLUORESCENCE MATERIAL Research & Business Foundation Sungkyunkwan University (KR) 2017-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170098779-A1 DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT EMITTING DEVICE HAVING THE DELAYED FLUORESCENCE MATERIAL HNRNPD, HNRNPDL, HNRNPF KDM4E 3504/4885NPSR1 4814/4885KMT2A 3653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.