SCHEMBL18700404

SCHEMBL18700404

CC1(C)c2ccccc2N(c2ccc(C#N)cc2C#N)c2c1ccc1c2oc2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ABCC9 O60706 1/20 0.32
PGR P06401 2/20 0.32
TNKS O95271 1/20 0.32
MEN1 O00255 1/20 0.30
CYP2C19 P33261 1/20 0.30
KMT2A Q03164 1/20 0.30
KDM4E B2RXH2 2/20 0.30
ALDH1A1 P00352 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18700409 0.90 MEN1 (0.32) PGRMEN1CYP2C19KMT2AKDM4E
SCHEMBL21945880 0.86 PGR (0.32) PGRMEN1CYP2C19KMT2AKDM4E
SCHEMBL15804139 0.81 KMT2A (0.41) PGRMEN1CYP2C19KMT2AKDM4E
SCHEMBL19345045 0.80 PGR (0.43) ABCC9PGRMEN1KMT2AKDM4E
SCHEMBL21946188 0.78 KDM4E (0.34) MEN1KMT2AKDM4EALDH1A1
SCHEMBL21946146 0.77 KDM4E (0.35) MEN1KMT2AKDM4EALDH1A1
SCHEMBL18700403 0.77 KDM4E (0.46) PGRMEN1CYP2C19KMT2AKDM4E
SCHEMBL21946192 0.76 PGR (0.32) PGR
SCHEMBL18700405 0.76 MEN1 (0.33) PGRMEN1CYP2C19KMT2AKDM4E
SCHEMBL21946184 0.75 KDM4E (0.34) MEN1KMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9882147-B2 Delayed fluorescence material and organic light emitting device having the delayed fluorescence material Research & Business Foundation Sungkyunkwan University (KR) 2018-01-30 US disclosed
US-20170098779-A1 DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT EMITTING DEVICE HAVING THE DELAYED FLUORESCENCE MATERIAL Research & Business Foundation Sungkyunkwan University (KR) 2017-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170098779-A1 DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT EMITTING DEVICE HAVING THE DELAYED FLUORESCENCE MATERIAL HNRNPD, HNRNPDL, HNRNPF ABCC9 688/4885PGR 3498/4885TNKS 2908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.