SCHEMBL18700930

SCHEMBL18700930

COc1ccc(S(=O)(=O)O)cc1Cl

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
SMN1; SMN2 Q16637 4/20 0.53
PTGS2 P35354 4/20 0.51
LMNA P02545 3/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
MAPT P10636 1/20 0.51
THRB P10828 1/20 0.51
HTT P42858 1/20 0.51
POLB P06746 3/20 0.50
RAB9A P51151 2/20 0.50
PTGS1 P23219 1/20 0.50
HPGD P15428 1/20 0.50
TSHR P16473 1/20 0.48
MAPK1 P28482 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28105953 0.98 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2PTGS2LMNAMEN1
SCHEMBL10498837 0.98 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2PTGS2LMNAMEN1
Nitrogen SCHEMBL28639385 0.96 ALDH1A1 (0.51) ALDH1A1SMN1; SMN2PTGS2LMNAMEN1
SCHEMBL18700933 0.85 TSHR (0.62) ALDH1A1SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL1178903 0.83 PTGS2 (0.53) ALDH1A1SMN1; SMN2PTGS2LMNAMEN1
SCHEMBL3493614 0.82 MAPK1 (0.70) ALDH1A1SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL29362862 0.82 MAPK1 (0.70) ALDH1A1SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL306820 0.82 ALDH1A1 (0.40) ALDH1A1SMN1; SMN2PTGS2KMT2AMAPT
SCHEMBL10172738 0.82 ALDH1A1 (0.40) ALDH1A1SMN1; SMN2PTGS2KMT2AMAPT
SCHEMBL2315314 0.81 PTGS2 (0.66) ALDH1A1PTGS2LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113502067-A Preparation method of direct blending dye 浙江闰土染料有限公司 2021-10-15 CN claimed
EP-3359620-B1 METHOD OF MONITORING A PARAMETER OF A HYDROCARBON WELL, PIPELINE OR FORMATION JOHNSON MATTHEY PLC (GB) 2022-11-30 EP disclosed
CN-113502067-A Preparation method of direct blending dye 浙江闰土染料有限公司 2021-10-15 CN disclosed
CN-113502067-A Preparation method of direct blending dye 浙江闰土染料有限公司 2021-10-15 CN disclosed
US-10365262-B2 Method of monitoring a parameter of a hydrocarbon well, pipeline or formation JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2019-07-30 US disclosed
US-20180284096-A1 METHOD OF MONITORING A PARAMETER OF A HYDROCARBON WELL, PIPELINE OR FORMATION TRACERCO LIMITED (GB) 2018-10-04 US disclosed
WO-2017060702-A1 METHOD OF MONITORING A PARAMETER OF A HYDROCARBON WELL, PIPELINE OR FORMATION JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2017-04-13 WO disclosed