Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18704088 | 1.00 | L3MBTL1 (0.60) | L3MBTL1HTTPOLBTDP1ALDH1A1 | |
| SCHEMBL23094258 | 0.83 | L3MBTL1 (0.70) | L3MBTL1HTTPOLBTDP1ALDH1A1 | |
| SCHEMBL10617882 | 0.78 | L3MBTL1 (0.55) | L3MBTL1HTTPOLBTDP1MEN1 | |
| SCHEMBL1990535 | 0.73 | CYP2C9 (0.57) | L3MBTL1HTTALDH1A1MEN1KMT2A | |
| SCHEMBL28858383 | 0.72 | FFAR1 (0.47) | L3MBTL1HTTTDP1MEN1KMT2A | |
| SCHEMBL8695372 | 0.72 | PLAAT3 (0.53) | L3MBTL1HTTMEN1KMT2AHTR3E | |
| SCHEMBL30495916 | 0.72 | TDP1 (0.50) | L3MBTL1HTTPOLBTDP1ALDH1A1 | |
| SCHEMBL5348317 | 0.72 | L3MBTL1 (0.49) | L3MBTL1HTTPOLBMEN1KMT2A | |
| SCHEMBL197699 | 0.72 | CYP11B1 (0.58) | L3MBTL1HTTPOLBALDH1A1MEN1 | |
| SCHEMBL4671096 | 0.70 | KMT2A (0.55) | L3MBTL1HTTTDP1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017060488-A1 | NEW TRPA1 ANTAGONISTS | ALMIRALL, S.A. (ES) | 2017-04-13 | — | — | WO | disclosed |