SCHEMBL1870423

SCHEMBL1870423

COC(=O)CCc1cc(-c2cccc3[nH]nnc23)c(O)c(C(C)(C)C)c1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 6/20 0.42
KMT2A Q03164 4/20 0.40
MEN1 O00255 3/20 0.40
ALDH1A1 P00352 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
LMNA P02545 1/20 0.38
AGTR1 P30556 1/20 0.38
HTT P42858 1/20 0.38
PTGS1 P23219 1/20 0.37
MAOB P27338 3/20 0.36
MAOA P21397 2/20 0.36
VCAM1 P19320 1/20 0.36
ACHE P22303 1/20 0.35
KDM4E B2RXH2 1/20 0.34
HPGD P15428 1/20 0.34
HSD17B10 Q99714 1/20 0.34
PTPN1 P18031 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5018040 0.85 KMT2A (0.40) GAAKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL2777243 0.85 GAA (0.34) GAAKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL6278572 0.85 ALDH1A1 (0.38) GAAKMT2AMEN1ALDH1A1LMNA
SCHEMBL5329783 0.83 GAA (0.40) GAAKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL29494854 0.83 PDE1A (0.34) GAAKMT2AMEN1ALDH1A1KDM4E
SCHEMBL5084394 0.83 PDE1A (0.34) GAAKMT2AMEN1ALDH1A1KDM4E
SCHEMBL29135489 0.82 GAA (0.34) GAAKMT2AMEN1ALDH1A1HTT
SCHEMBL4887850 0.82 CYP3A4 (0.39) GAAKMT2AMEN1ALDH1A1LMNA
SCHEMBL3006059 0.82 GAA (0.44) GAAKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL10482112 0.81 GAA (0.32) GAAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114616264-B Oligomer or polymer, composition, use of oligomer or polymer and intermediate 弗劳恩霍夫应用研究促进协会 2024-03-01 CN disclosed
CN-116075429-A Thermally reflective film with improved mechanical properties and high weatherability 罗姆化学有限责任公司 2023-05-05 CN disclosed
CN-115968390-A Coating liquid for forming pressure measurement layer, method for producing pressure measurement layer, and non-planar part-containing article with pressure measurement layer 富士胶片株式会社 2023-04-14 CN disclosed
CN-115461396-A Additive composition and use thereof, condensation polymer composition, moulding compound and moulded part produced therefrom and use thereof 弗劳恩霍夫应用研究促进协会 2022-12-09 CN disclosed
CN-115260650-A Plastic composition containing at least one metal pigment, method for the production thereof and use thereof 埃卡特有限公司 2022-11-01 CN disclosed
EP-4069757-A1 FLAME RETARDANT POLYMER COMPRISING PHOSPHORUS-CONTAINING REPEATING UNITS, PLASTIC COMPOSITION COMPRISING THE FLAME RETARDANT POLYMER, PROCESS FOR PRODUCING THE FLAME RETARDANT POLYMER AND USE THEREOF Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2022-10-12 EP disclosed
CN-109153915-B Polymerizable liquid crystal material and polymerized liquid crystal film 默克专利股份有限公司 2022-09-23 CN disclosed
CN-114616264-A Oligomer or polymer, composition, use of oligomer or polymer and intermediate 弗劳恩霍夫应用研究促进协会 2022-06-10 CN disclosed
CN-114606012-A Polymerizable liquid crystal material and polymerized liquid crystal film 默克专利股份有限公司 2022-06-10 CN disclosed
CN-114517098-A Polymerizable liquid crystal material and polymerized liquid crystal film 默克专利股份有限公司 2022-05-20 CN disclosed
US-20070015870-A1 Sulfoxides or sulfones grafted onto polymers CIBA CORPORATION 2007-01-18 US disclosed
CN-1531567-A Polycarbonates with significant shear thinning behavior 2004-09-22 CN disclosed
CN-1501952-A Polycarbonates having a low shear thinning ratio 2004-06-02 CN disclosed
EP-1268642-A1 SYNERGISTIC COMBINATIONS OF PHENOLIC ANTIOXIDANTS Clariant Finance (BVI) Limited (VG) 2003-01-02 EP disclosed
WO-2001062839-A1 SYNERGISTIC COMBINATIONS OF PHENOLIC ANTIOXIDANTS CLARIANT FINANCE (BVI) LIMITED (VG) 2001-08-30 WO disclosed
EP-1089985-A1 RED-SHIFTED TRISARYL-1,3,5-TRIAZINE ULTRAVIOLET LIGHT ABSORBERS CYTEC TECHNOLOGY CORP. (US) 2001-04-11 EP disclosed
WO-1999067224-A1 RED-SHIFTED TRISARYL-1,3,5-TRIAZINE ULTRAVIOLET LIGHT ABSORBERS CYTEC TECHNOLOGY CORP. (US) 1999-12-29 WO disclosed
US-5844024-A Cyclic diphenylacetonitriles as stabilizers CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-12-01 US disclosed
US-5770643-A Pyrrolodiazine derivatives as stabilizers for chlorine-containing polymers CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-06-23 US disclosed
US-5459222-A UV-absorbing polyurethanes and polyesters CIBA-GEIGY CORPORATION 1995-10-17 US disclosed