SCHEMBL2777243

SCHEMBL2777243

C=CC(=O)OCCOC(=O)CCc1cc(-c2cccc3[nH]nnc23)c(O)c(C(C)(C)C)c1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GAA P10253 6/20 0.34
ALOX5 P09917 1/20 0.34
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
THRB P10828 1/20 0.32
XBP1 P17861 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
GPR55 Q9Y2T6 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
AGTR1 P30556 1/20 0.30
HTT P42858 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10482112 0.89 GAA (0.32) GAAKMT2AMEN1
SCHEMBL6278572 0.86 ALDH1A1 (0.38) GAAALOX5KMT2AMEN1ALDH1A1
SCHEMBL1870423 0.85 GAA (0.42) GAAKMT2AMEN1ALDH1A1LMNA
SCHEMBL10394409 0.85 MAOB (0.31) GAAKMT2AMEN1
SCHEMBL29494854 0.84 PDE1A (0.34) GAAALOX5KMT2AMEN1ALDH1A1
SCHEMBL5084394 0.84 PDE1A (0.34) GAAALOX5KMT2AMEN1ALDH1A1
SCHEMBL28644704 0.80 GAA (0.33) GAAKMT2AMEN1
SCHEMBL4887850 0.79 CYP3A4 (0.39) GAAKMT2AMEN1XBP1NPSR1
SCHEMBL2612492 0.79 GAA (0.51) GAAALOX5KMT2AMEN1THRB
SCHEMBL6851614 0.77 APP (0.39) GAAALOX5KMT2AMEN1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7622185-B2 Protective cover sheet comprising a UV-absorbing layer for a polarizer plate and method of making the same NITTO DENKO CORPORATION (JP) 2009-11-24 US claimed
WO-2006113164-A1 UV-ABSORBING LAYER FOR POLARIZER PLATE NITTO DENKO CORPORATION (JP) 2006-10-26 WO claimed
US-20060234035-A1 Protective cover sheet comprising a UV-absorbing layer for a polarizer plate and method of making the same EASTMAN KODAK COMPANY 2006-10-19 US claimed
WO-2020189390-A1 ADHESIVE AGENT COMPOSITION, ADHESIVE AGENT LAYER, AND ADHESIVE SHEET 日東電工株式会社 2020-09-24 WO disclosed
US-8709192-B2 Protective cover sheet comprising a UV-absorbing layer for a polarizer plate and method of making the same NITTO DENKO CORPORATION (JP) 2014-04-29 US disclosed
US-20130083273-A1 SURFACE FILM FOR IMAGE DISPLAY DEVICE, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2013-04-04 US disclosed
US-8208197-B2 Optical film, and polarizing plate and liquid crystal display device using the optical film FUJIFILM CORPORATION (JP) 2012-06-26 US disclosed
US-8194210-B2 Polarizing plate protective film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-06-05 US disclosed
US-20100024969-A1 PROTECTIVE COVER SHEET COMPRISING A UV-ABSORBING LAYER FOR A POLARIZER PLATE AND METHOD OF MAKING THE SAME NITTO DENKO CORPORATION (JP) 2010-02-04 US disclosed
US-20100020396-A1 POLARIZER PROTECTIVE FILM, POLARIZING PLATE, AND IMAGE DISPLAY APPARATUS NIPPON SHOKUBAI CO., LTD. (JP) 2010-01-28 US disclosed
US-7622185-B2 Protective cover sheet comprising a UV-absorbing layer for a polarizer plate and method of making the same NITTO DENKO CORPORATION (JP) 2009-11-24 US disclosed
US-20080100780-A1 POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2008-05-01 US disclosed
WO-2006113164-A1 UV-ABSORBING LAYER FOR POLARIZER PLATE NITTO DENKO CORPORATION (JP) 2006-10-26 WO disclosed
US-20060234035-A1 Protective cover sheet comprising a UV-absorbing layer for a polarizer plate and method of making the same EASTMAN KODAK COMPANY 2006-10-19 US disclosed
EP-1357145-B1 Transparent resin laminate and molded article incorporating the same MITSUBISHI GAS CHEMICAL CO (JP) 2006-05-10 EP disclosed
EP-1059175-B1 A thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-04-21 EP disclosed
US-6645910-B1 Ultraviolet radiation absorber emulsion polymer comprising unsaturated derivatives of 2-hydroxybenzophenone and 2-(2*-hydroxyphenyl)benzotriazole as comonomers; colorless basic leuco dye NIPPON PAPER INDUSTRIES CO. LTD. (JP) 2003-11-11 US disclosed
EP-1357145-A1 Transparent resin laminate and molded article incorporating the same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2003-10-29 EP disclosed
US-6620509-B1 Polycarbonate resin base; acrylic resin layer; ultraviolet absorbent coated on one surface of polycarbonate and a cured layer of polyorganosiloxane and a silicone-containing polymer ultraviolet absorbent on acrylic resin are cured MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2003-09-16 US disclosed
EP-1059175-A2 A thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-12-13 EP disclosed