Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 13/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23209149 | 0.88 | TRPA1 (0.53) | TRPA1NOTUMMAPT | |
| SCHEMBL23209150 | 0.88 | TRPA1 (0.53) | TRPA1NOTUMMAPT | |
| SCHEMBL18703974 | 0.81 | TRPA1 (0.46) | TRPA1NOTUM | |
| SCHEMBL24682180 | 0.81 | TRPA1 (0.50) | TRPA1NOTUM | |
| SCHEMBL18704156 | 0.79 | TRPA1 (0.52) | TRPA1MAPT | |
| SCHEMBL6980080 | 0.78 | MAPT (0.57) | NOTUMMAPT | |
| SCHEMBL31678530 | 0.78 | TRPA1 (0.61) | TRPA1 | |
| SCHEMBL26888448 | 0.77 | TRPA1 (0.55) | TRPA1 | |
| SCHEMBL31678489 | 0.77 | TRPA1 (0.68) | TRPA1 | |
| SCHEMBL25969158 | 0.77 | TRPA1 (0.55) | TRPA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017060488-A1 | NEW TRPA1 ANTAGONISTS | ALMIRALL, S.A. (ES) | 2017-04-13 | — | — | WO | disclosed |