Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11865429 | 0.88 | ERCC5 (0.57) | CYP3A4SMN1; SMN2PKMNPSR1ERCC5 | |
| Valine SCHEMBL16464110 | 0.85 | SMN1; SMN2 (0.40) | CYP3A4KMT2AHPGDSMN1; SMN2MEN1 | |
| SCHEMBL11556841 | 0.83 | ERCC5 (0.53) | CYP3A4KMT2AHPGDSMN1; SMN2MEN1 | |
| SCHEMBL16748942 | 0.83 | PLOD2 (0.47) | CYP3A4KMT2AHPGDSMN1; SMN2MEN1 | |
| SCHEMBL9858678 | 0.83 | MEN1 (0.49) | CYP3A4KMT2AHPGDSMN1; SMN2MEN1 | |
| SCHEMBL7668299 | 0.80 | SMN1; SMN2 (0.46) | CYP3A4KMT2AHPGDSMN1; SMN2MEN1 | |
| SCHEMBL978354 | 0.80 | CYP3A4 (0.53) | CYP3A4KMT2ASMN1; SMN2MEN1MAPK1 | |
| SCHEMBL9632069 | 0.79 | GLA (0.56) | CYP3A4KMT2AHPGDSMN1; SMN2MEN1 | |
| SCHEMBL28343462 | 0.78 | CYP3A4 (0.69) | CYP3A4KMT2ASMN1; SMN2MEN1MAPK1 | |
| Benzene SCHEMBL28207781 | 0.78 | CYP3A4 (0.69) | CYP3A4KMT2ASMN1; SMN2MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4687857-A | Alkyl β-oxo-benzenepropanoates | Uclaf, Roussel (FR) | 1987-08-18 | — | — | US | claimed |
| EP-0220923-A2 | Dipeptides and process | W.R. Grace & Co.-Conn. (US) | 1987-05-06 | — | — | EP | claimed |
| CN-111269425-B | Modified MQ resin and preparation method and application thereof | 浙江新安化工集团股份有限公司 | 2021-05-28 | — | — | CN | disclosed |
| EP-2211602-B1 | LIGHTWEIGHT COMPOSITE ARTICLE WITH CONTROLLED BIODEGRADATION | UNIV MAINE SYSTEM (US) | 2021-02-03 | — | — | EP | disclosed |
| CN-111269425-A | Modified MQ resin and preparation method and application thereof | 浙江新安化工集团股份有限公司 | 2020-06-12 | — | — | CN | disclosed |
| US-10433543-B2 | Bioactive biopolymer films and coatings | TERRAVERDAE BIOWORKS INC. (CA) | 2019-10-08 | — | — | US | disclosed |
| US-9951034-B2 | 3-ketocoumarines for LED photocuring | IGM RESINS ITALIA S.R.L. (IT) | 2018-04-24 | — | — | US | disclosed |
| US-20170245494-A1 | BIOACTIVE BIOPOLYMER FILMS AND COATINGS | TERRAVERDAE BIOWORKS INC. (CA) | 2017-08-31 | — | — | US | disclosed |
| EP-2909243-B1 | 3-KETOCOUMARINES FOR LED PHOTOCURING | IGM RESINS ITALIA SRL (IT) | 2016-11-30 | — | — | EP | disclosed |
| WO-2016058096-A1 | BIOACTIVE BIOPOLYMER FILMS AND COATINGS | TERRAVERDAE BIOWORKS INC. (CA) | 2016-04-21 | — | — | WO | disclosed |
| US-20150259316-A1 | 3-KETOCOUMARINES FOR LED PHOTOCURING | ELIOS S.R.L. (IT) | 2015-09-17 | — | — | US | disclosed |
| US-4412958-A | Stereospecific synthesis of 5-phenyl-2S-pentanol | PFIZER INC. (US) | 1983-11-01 | — | — | US | disclosed |
| EP-0079134-A1 | Stereospecific synthesis of 5-phenyl-2S-pentanol | PFIZER INC. (US) | 1983-05-18 | — | — | EP | disclosed |
| US-4156666-A | HOMO- OR COPOLYMER OF ETHYLENE OR PROPYLENE, A DEGRADATION PROMOTER AND AN INORGANIC FILLER | SHISEIDO COMPANY, LTD. (JP) | 1979-05-29 | — | — | US | disclosed |
| US-4151302-A | Araliphatic dihalogen compounds composition and method of use | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-04-24 | — | — | US | disclosed |
| US-4115570-A | CENTRAL NERVOUS SYSTEM DEPRESSANTS | ISTITUTO CHEMIOTERAPICO ITALIANO, S.P.A. (IT) | 1978-09-19 | — | — | US | disclosed |
| US-4088758-A | INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |
| US-4057647-A | Araliphatic dihalogen compounds and process for their preparation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-11-08 | — | — | US | disclosed |
| US-4032634-A | O,O-DIALKYL-O-(1-PHENYL-2-CARBALKOXYVINYL)-THIONOPHOSPHORIC ACID ESTERS AND INSECTICIDAL AND ACARICIDAL COMPOSITIONS AND METHOD OF USE THEREOF | BAYER AKTIENGESELLSCHAFT (DT) | 1977-06-28 | — | — | US | disclosed |
| US-4024123-A | TEXTILES | DUSSY PAUL | 1977-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150259316-A1 | 3-KETOCOUMARINES FOR LED PHOTOCURING | KDM3A, KMO, HCCS | CYP3A4 38/4885KMT2A 330/4885HPGD 222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.