Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 3/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.48 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.48 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.48 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.44 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 2/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | GIGYF2 | Q6Y7W6 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20520180 | 0.91 | PRSS1 (0.55) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL18705362 | 0.90 | CSNK2A2 (0.54) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL20519818 | 0.89 | FOLH1 (0.53) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL20520038 | 0.87 | CSNK2A2 (0.51) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL20520124 | 0.86 | CSNK2A2 (0.54) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL18705366 | 0.86 | CSNK2A2 (0.46) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL18705334 | 0.85 | F2 (0.48) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL18705379 | 0.82 | CSNK2A2 (0.48) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL20519968 | 0.82 | FOLH1 (0.60) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL29832821 | 0.81 | PKM (0.56) | PRSS1PRSS2PRSS3TPSAB1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017060729-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | CENTAURI THERAPEUTICS LIMITED (GB) | 2017-04-13 | — | — | WO | disclosed |