Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.45 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | IDE | P14735 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18705368 | 0.93 | FOLH1 (0.46) | CSNK2A2CSNK2BCSNK2A1CAMK2BF2 | |
| SCHEMBL18705334 | 0.90 | F2 (0.48) | CSNK2A2CSNK2BCSNK2A1CAMK2BF2 | |
| SCHEMBL20519904 | 0.86 | FOLH1 (0.59) | CSNK2A2CSNK2BCSNK2A1CAMK2BF2 | |
| SCHEMBL18705384 | 0.86 | PRSS1 (0.48) | CSNK2A2CSNK2BCSNK2A1CAMK2BF2 | |
| SCHEMBL18736240 | 0.85 | FOLH1 (0.58) | CSNK2A2CSNK2BCSNK2A1CAMK2BF2 | |
| SCHEMBL18736244 | 0.84 | TDP1 (0.56) | CSNK2A2CSNK2BCSNK2A1CAMK2BF2 | |
| SCHEMBL18705369 | 0.84 | GIGYF2 (0.47) | CSNK2A2CSNK2BCSNK2A1CAMK2BF2 | |
| SCHEMBL20519968 | 0.82 | FOLH1 (0.60) | CSNK2A2CSNK2BCSNK2A1CAMK2BF2 | |
| SCHEMBL23125939 | 0.81 | TDP1 (0.51) | CSNK2A2CSNK2BCSNK2A1CAMK2BF2 | |
| SCHEMBL18705346 | 0.81 | TDP1 (0.53) | CSNK2A2CSNK2BCSNK2A1CAMK2BF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017060729-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | CENTAURI THERAPEUTICS LIMITED (GB) | 2017-04-13 | — | — | WO | disclosed |