Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL278340 | 0.86 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL26843211 | 0.72 | — | — | |
| SCHEMBL12854259 | 0.70 | CRHBP (0.38) | ALDH1A1 | |
| SCHEMBL13242280 | 0.70 | NPSR1 (0.31) | ALDH1A1 | |
| SCHEMBL13661983 | 0.70 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL24021303 | 0.69 | POLB (0.36) | ALDH1A1 | |
| SCHEMBL24073848 | 0.69 | — | — | |
| SCHEMBL270897 | 0.68 | NPSR1 (0.44) | — | |
| SCHEMBL1118150 | 0.68 | NPSR1 (0.44) | — | |
| SCHEMBL16472610 | 0.67 | MAPT (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611260-B2 | Compositions and methods for inhibition of the JAK pathway | RIGEL PHARMACEUTICALS, INC. (US) | 2017-04-04 | — | — | US | disclosed |