Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13633786 | 0.81 | ALDH1A1 (0.46) | ALDH1A1KDM4ELMNAGAAMEN1 | |
| SCHEMBL13633776 | 0.75 | ALDH1A1 (0.54) | ALDH1A1KDM4ELMNAGAAMEN1 | |
| SCHEMBL5476168 | 0.74 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNAGAAMEN1 | |
| SCHEMBL14439025 | 0.74 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNAGAAMEN1 | |
| SCHEMBL5123808 | 0.71 | ALDH1A1 (0.51) | ALDH1A1KDM4ELMNAGAAMEN1 | |
| SCHEMBL12618444 | 0.71 | HDAC4 (0.43) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL5109589 | 0.69 | KDM4E (0.62) | ALDH1A1KDM4ELMNAGAAMEN1 | |
| SCHEMBL3758086 | 0.69 | KDM4E (0.51) | ALDH1A1KDM4EGAANPC1HPGD | |
| SCHEMBL14864788 | 0.69 | ALDH1A1 (0.36) | ALDH1A1KDM4ELMNAGAAMEN1 | |
| SCHEMBL19135713 | 0.69 | PGR (0.42) | ALDH1A1KDM4ELMNAGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051961-A1 | COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND RELATED DISEASES | CADILA HEALTHCARE LIMITED (IN) | 2011-05-05 | — | — | WO | disclosed |
| CN-1471517-A | OXAZOLYL-arylpropionic acid derivatives and their sue as PPAR agonists | — | 2004-01-28 | — | — | CN | disclosed |