Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | CASP3 | P42574 | 2/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | IL6 | P05231 | 2/20 | 0.45 |
| ▸ | STAT3 | P40763 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9884980 | 0.89 | NPC1 (0.65) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL9380371 | 0.81 | PIK3CA (0.51) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL15450923 | 0.81 | PIK3CA (0.51) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL7901113 | 0.79 | NPC1 (0.50) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL29957899 | 0.77 | PIK3CA (0.48) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL21389696 | 0.77 | PIK3CA (0.48) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL7898012 | 0.77 | PIK3CA (0.48) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL179548 | 0.77 | PIK3CA (0.51) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL4477605 | 0.75 | RAB9A (0.61) | NPC1RAB9APIK3CAMAPTMEN1 | |
| SCHEMBL4474238 | 0.75 | PIK3CA (0.52) | NPC1RAB9ACASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150609-A1 | PROCESS FOR PREPARING CERTAIN CHEMICAL ENTITIES | Intellikine, LLC (US) | 2017-04-05 | — | — | EP | disclosed |