Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | METAP2 | P50579 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | HCK | P08631 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18257315 | 0.80 | IDO1 (0.43) | IDO1METAP2TDO2PDPK1CYP1A2 | |
| SCHEMBL685418 | 0.76 | IDO1 (0.59) | IDO1METAP2TDO2PIK3CDABL1 | |
| SCHEMBL3538351 | 0.75 | METAP2 (0.56) | IDO1METAP2TDO2PIK3CDABL1 | |
| SCHEMBL30403358 | 0.75 | METAP2 (0.56) | IDO1METAP2TDO2PIK3CDABL1 | |
| SCHEMBL30861059 | 0.73 | LRRK2 (0.54) | CYP1A2FLT3 | |
| SCHEMBL27227968 | 0.73 | LRRK2 (0.54) | CYP1A2FLT3 | |
| SCHEMBL14737953 | 0.72 | METAP2 (0.53) | IDO1METAP2TDO2CYP1A2AXL | |
| SCHEMBL12683697 | 0.72 | FGFR1 (0.44) | IDO1METAP2TDO2PIK3CDABL1 | |
| SCHEMBL18062618 | 0.72 | IDO1 (0.47) | IDO1METAP2TDO2PIK3CDABL1 | |
| SCHEMBL1318814 | 0.72 | TDO2 (0.61) | IDO1METAP2TDO2AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150609-A1 | PROCESS FOR PREPARING CERTAIN CHEMICAL ENTITIES | Intellikine, LLC (US) | 2017-04-05 | — | — | EP | disclosed |