Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | KDM1A | O60341 | 3/20 | 0.63 |
| ▸ | MAOA | P21397 | 3/20 | 0.63 |
| ▸ | MAOB | P27338 | 3/20 | 0.63 |
| ▸ | MGLL | Q99685 | 2/20 | 0.63 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.62 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MIF | P14174 | 1/20 | 0.56 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9128045 | 0.95 | ROCK2 (0.69) | POLBTP53MAPTKDM1AMAOA | |
| Benzyl Phenylcarbamate SCHEMBL1222943 | 0.91 | POLB (0.78) | POLBTP53MAPTKDM1AMAOA | |
| SCHEMBL9125031 | 0.89 | SMN1; SMN2 (0.59) | POLBTP53MAPTKDM1AMAOA | |
| SCHEMBL10598558 | 0.88 | POLB (0.69) | POLBTP53MAPTKDM1AMAOA | |
| SCHEMBL10595799 | 0.87 | POLB (0.73) | POLBTP53MAPTKDM1AMAOA | |
| SCHEMBL97634 | 0.87 | POLB (0.68) | POLBTP53MAPTKDM1AMAOA | |
| SCHEMBL3795024 | 0.87 | POLB (0.68) | POLBTP53MAPTKDM1AMAOA | |
| SCHEMBL3694153 | 0.87 | POLB (0.68) | POLBTP53MAPTKDM1AMAOA | |
| SCHEMBL7663567 | 0.87 | POLB (0.68) | POLBTP53MAPTKDM1AMAOA | |
| SCHEMBL5700992 | 0.87 | POLB (0.68) | POLBTP53MAPTKDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1091432-A | Can suppress the active peptide of hiv protease, its preparation with and medical use | SANKYO CO (JP) | 1994-08-31 | — | — | CN | claimed |
| US-20260000609-A1 | METHODS AND COMPOSITIONS FOR TARGETED DELIVERY BY POLYMERSOMES | ROCK BIOMEDICAL INC (TW) | 2026-01-01 | — | — | US | disclosed |
| EP-4568709-A2 | METHODS AND COMPOSITIONS FOR TARGETED DELIVERY BY POLYMERSOMES | Rock Biomedical Inc. (TW) | 2025-06-18 | — | — | EP | disclosed |
| US-12318485-B2 | Methods and compositions for targeted delivery by polymersomes | ROCK BIOMEDICAL, INC. (TW) | 2025-06-03 | — | — | US | disclosed |
| US-20250041222-A1 | METHODS AND COMPOSITIONS FOR TARGETED DELIVERY BY POLYMERSOMES | ROCK BIOMEDICAL INC. (TW) | 2025-02-06 | — | — | US | disclosed |
| CN-119080631-A | Method for preparing N-aryl amide compound by catalyzing nitrite-mediated selenium | 浙江工业大学 | 2024-12-06 | — | — | CN | disclosed |
| CN-118880357-A | Benzoxazine derivative and electrochemical synthesis method thereof | 齐齐哈尔医学院 | 2024-11-01 | — | — | CN | disclosed |
| WO-2024215612-A2 | METHODS AND COMPOSITIONS FOR TARGETED DELIVERY BY POLYMERSOMES | ROC BIOMEDICAL INC. (TW) | 2024-10-17 | — | — | WO | disclosed |
| CN-116283916-B | Compound with Axl and c-Met kinase inhibition activity and preparation and application thereof | 中国科学院上海药物研究所 | 2024-06-11 | — | — | CN | disclosed |
| US-20240124491-A1 | METHODS AND COMPOUNDS FOR TREATING FRIEDREICH'S ATAXIA | Design Therapeutics, Inc. | 2024-04-18 | — | — | US | disclosed |
| WO-2000023076-A1 | AMINOPHENOXYACETIC ACID DERIVATIVES AS NEUROPROTECTANTS | SUNTORY LIMITED (JP) | 2000-04-27 | — | — | WO | disclosed |
| CN-1246110-A | Arylpiperidinopropanol and arylpiperazinopropanol derivatives and drugs containing the same | SUNTORY LTD (JP) | 2000-03-01 | — | — | CN | disclosed |
| EP-0958280-A1 | ARYLPIPERIDINOPROPANOL AND ARYLPIPERAZINOPROPANOL DERIVATIVES AND PHARMACEUTICALS CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1999-11-24 | — | — | EP | disclosed |
| WO-1999023072-A1 | ARYLPIPERIDINOPROPANOL AND ARYLPIPERAZINOPROPANOL DERIVATIVES AND PHARMACEUTICALS CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1999-05-14 | — | — | WO | disclosed |
| EP-0632019-B1 | Acylureas | ZENECA LTD (GB) | 1997-09-24 | — | — | EP | disclosed |
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| US-5576334-A | ANTICOAGULANTS | ZENECA LIMITED (GB) | 1996-11-19 | — | — | US | disclosed |
| EP-0632019-A1 | Acylureas | ZENECA LIMITED (GB) | 1995-01-04 | — | — | EP | disclosed |
| CN-1091432-A | Can suppress the active peptide of hiv protease, its preparation with and medical use | SANKYO CO (JP) | 1994-08-31 | — | — | CN | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240124491-A1 | METHODS AND COMPOUNDS FOR TREATING FRIEDREICH'S ATAXIA | ATXN2, ATXN2L, CDR2 | POLB 45/4885TP53 2399/4885MAPT 2092/4885 |
| US-12318485-B2 | Methods and compositions for targeted delivery by polymersomes | ALG1, CHMP4B, ALG8 | POLB 96/4885TP53 847/4885MAPT 629/4885 |
| US-20260000609-A1 | METHODS AND COMPOSITIONS FOR TARGETED DELIVERY BY POLYMERSOMES | CD2, CLEC4M, CD47 | POLB 2622/4885TP53 994/4885MAPT 1026/4885 |
| US-20250041222-A1 | METHODS AND COMPOSITIONS FOR TARGETED DELIVERY BY POLYMERSOMES | ALG1, CHMP4B, ALG8 | POLB 96/4885TP53 847/4885MAPT 629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.