Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 14/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 14/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL327593 | 0.89 | HPGD (0.44) | HPGDHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL15994284 | 0.82 | HPGD (0.38) | HPGDHDAC1HDAC2ALDH1A1HSD17B10 | |
| SCHEMBL28851780 | 0.79 | HPGD (0.55) | HPGDHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL16279734 | 0.79 | HCRTR1 (0.33) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL16279731 | 0.79 | RAB9A (0.38) | HPGDHDAC3HDAC6ALDH1A1LMNA | |
| SCHEMBL155342 | 0.78 | HPGD (0.57) | HPGDHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL29380577 | 0.78 | HPGD (0.57) | HPGDHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL19444563 | 0.77 | HPGD (0.56) | HPGDHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL31005444 | 0.77 | HPGD (0.42) | HPGDHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL43173 | 0.77 | HPGD (0.42) | HPGDHDAC1HDAC2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496265-A1 | VACCINE COMPOSITIONS AND METHODS OF USE | Orbis Health Solutions LLC (US) | 2012-09-12 | — | — | EP | disclosed |
| WO-2011053331-A1 | VACCINE COMPOSITIONS AND METHODS OF USE | ORBIS HEALTH SOLUTIONS LLC (US) | 2011-05-05 | — | — | WO | disclosed |
| US-20100111985-A1 | VACCINE COMPOSITIONS AND METHODS OF USE | ORBIS HEALTH SOLUTIONS, LLC | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100111985-A1 | VACCINE COMPOSITIONS AND METHODS OF USE | CD47, MYD88, CD14 | HPGD 1879/4885HDAC1 4541/4885HDAC2 4574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.