Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16499846 | 0.74 | APLNR (0.32) | APLNR | |
| SCHEMBL26556218 | 0.72 | APLNR (0.31) | APLNR | |
| SCHEMBL9991970 | 0.72 | TSHR (0.39) | APLNR | |
| SCHEMBL25001313 | 0.72 | APLNR (0.39) | APLNR | |
| SCHEMBL1933726 | 0.72 | APLNR (0.31) | APLNR | |
| SCHEMBL1933922 | 0.70 | TSHR (0.37) | APLNR | |
| SCHEMBL21904698 | 0.69 | APLNR (0.35) | APLNR | |
| SCHEMBL26869804 | 0.69 | — | — | |
| SCHEMBL23183520 | 0.69 | APLNR (0.33) | APLNR | |
| SCHEMBL19115012 | 0.67 | JAK2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150600-B1 | DIHYDROPYRIMIDO LOOP DERIVATIVE AS HBV INHIBITOR | QILU PHARMACEUTICAL CO LTD (CN) | 2018-06-27 | — | — | EP | disclosed |
| EP-3150600-A1 | DIHYDROPYRIMIDO LOOP DERIVATIVE AS HBV INHIBITOR | Medshine Discovery Inc. (CN) | 2017-04-05 | — | — | EP | disclosed |