Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20609946 | 0.73 | APLNR (0.39) | APLNR | |
| SCHEMBL20609919 | 0.70 | CXCR2 (0.30) | — | |
| SCHEMBL25001313 | 0.69 | APLNR (0.39) | APLNRCA1 | |
| SCHEMBL18709642 | 0.69 | APLNR (0.33) | APLNR | |
| SCHEMBL20609939 | 0.67 | GRM2 (0.32) | — | |
| SCHEMBL23062926 | 0.67 | APLNR (0.37) | APLNRCA1CA2 | |
| SCHEMBL20609894 | 0.66 | — | — | |
| SCHEMBL20609836 | 0.66 | — | — | |
| SCHEMBL14033223 | 0.64 | — | — | |
| SCHEMBL244348 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200138811-A1 | Chemical Compounds | AVISTA PHARMA SOLUTIONS INC (US) | 2020-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200138811-A1 | Chemical Compounds | JAK1, JAK3, JAK2 | APLNR 3319/4885CA1 3104/4885CA2 1016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.