Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 5/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | ESRRB | O95718 | 1/20 | 0.31 |
| ▸ | ESRRA | P11474 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22193121 | 0.75 | HSD17B10 (0.47) | CYP19A1MAOBHSP90AA1ALDH1A1 | |
| SCHEMBL23683711 | 0.75 | MEN1 (0.31) | — | |
| SCHEMBL23425343 | 0.71 | MEN1 (0.37) | HSP90AA1 | |
| SCHEMBL22651668 | 0.70 | HSD17B10 (0.31) | HSP90AA1 | |
| SCHEMBL28793740 | 0.63 | MAOA (0.38) | TYRCYP19A1MAOBESR2HSP90AA1 | |
| SCHEMBL29083061 | 0.62 | ESR2 (0.59) | ESR1ESR2RAB9A | |
| SCHEMBL5981511 | 0.60 | ESR2 (0.75) | ESR1PTPN1ESR2RAB9A | |
| SCHEMBL12326180 | 0.60 | CA1 (0.50) | RAB9AALDH1A1 | |
| SCHEMBL16804614 | 0.59 | RAB9A (0.38) | TYRPTGS2CYP19A1MAOBRAB9A | |
| SCHEMBL24181236 | 0.59 | ESR2 (0.62) | MAOBESR1ESR2HSP90AA1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9688857-B2 | Fluorescent probe | THE UNIVERSITY OF TOKYO (JP) | 2017-06-27 | — | — | US | disclosed |
| US-20170096561-A1 | FLUORESCENT PROBE | THE UNIVERSITY OF TOKYO (JP) | 2017-04-06 | — | — | US | disclosed |